※ dbPPT Protein Information
| Tag | Content | ||||||||||||||||||||||||||||||
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 8.52 | ||||||||||||||||||||||||||||||
Molecular Weight | 34974.94 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Uricase; Urate oxidase | ||||||||||||||||||||||||||||||
Gene Name | |||||||||||||||||||||||||||||||
Created Date | 2007-03-06 | ||||||||||||||||||||||||||||||
Organism | Medicago truncatula(Barrel medic Medicago tribuloides) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 3880 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin (By similarity). Sequence Annotation region of interest 237 238 Substrate binding short sequence motif 306 308 Microbody targeting signal (Potential) active site 182 Charge relay system active site 238 Charge relay system binding site 182 Substrate Keyword Oxidoreductase,Peroxisome,Purine metabolism Sequence Source UniProt Protein Sequence MAKNVEGFEF EQRHGKERVR VARVWKSKDG KQQFVVEWRV SINLLSDCVN SYVRDDNSDI 60 VATDTMKNTV YAKAKECSEI LSVEDFAILL AKHFTSFYSQ VTTAIVKIVE KPWERVNVDG 120 QPHDHGFKLG SEKHTTEAIV KKSGALQLTS GIEGLSVLKT TKSGFEGFVR DKYTILPDTR 180 ERMLATEVTA LWRYSYESLY SVPKKPLYFT EKYLDVKRVL LDTFFGSPKE GVYSPSVQAT 240 LYQMAKAALN RFPDIASIQL KMPNIHFIPV NLSNKNGQFV KFDDDVYLPT DEPHGSIEAS 300 LSCSRSKM 308 Gene Ontology GO:0005777; C: peroxisome; IEA: UniProtKB-SubCell GO:0004846; F: urate oxidase activity; IEA: UniProtKB-EC GO:0006144; P: purine nucleobase metabolic process; IEA: UniProtKB-KW GO:0019628; P: urate catabolic process; IEA: UniProtKB-UniPathway Interpro Pfam Pfam; PF01014; Uricase SMART PROSITE PS00366; URICASE PRINTS PR00093; URICASE |