※ dbPPT Protein Information
| Tag | Content | ||||||||||||||||||||||||||||||
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 6.03 | ||||||||||||||||||||||||||||||
Molecular Weight | 42583.56 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | S-adenosylmethionine synthase; AdoMet synthase; Methionine adenosyltransferase; MAT | ||||||||||||||||||||||||||||||
Gene Name | METM; CHLREDRAFT_182408 | ||||||||||||||||||||||||||||||
Created Date | 2009-02-10 | ||||||||||||||||||||||||||||||
Organism | Chlamydomonas reinhardtii(Chlamydomonas smithii) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 3055 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (By similarity). Sequence Annotation chain 1 390 S-adenosylmethionine synthase nucleotide phosphate-binding region 122 127 ATP nucleotide phosphate-binding region 270 277 ATP metal ion-binding site 20 Magnesium metal ion-binding site 46 Potassium metal ion-binding site 274 Potassium metal ion-binding site 282 Magnesium Keyword ATP-binding,Cobalt,Complete proteome,Cytoplasm,Magnesium,Metal-binding,Nucleotide-binding,One-carbon metabolism,Potassium,Reference proteome,Transferase Sequence Source UniProt Protein Sequence MAALESFLYT SESVNEGHPD KICDQVSDAV LDACLEQDPD SKVACETCCK TGMVMVFGEI 60 TTKAKVDYEA IVRKVCKEIG FTSEDVGLDA DKCKVLVHIE EQSPDIGQGV HGMGTKALEE 120 IGAGDQGHMF GYATDETPEL MPLTHVLATQ LGYKLTEVRK NGVCPWLRPD GKTQVTVEYK 180 REGGAMIPQR VHTILISTQH NPDVTNEKIR EDLMEHVIKP VVPAKYLDDK TIFHLNPSGR 240 FVIGGPHGDA GLTGRKIIID TYGGWGAHGG GAFSGKDPTK VDRSGAYIAR QAAKSVVASG 300 LAKRCLVQVS YSIAVAEPLS VFVDTYGTGT MPDAEILKLI RKHFDFRPGL IGKNLDLKRG 360 GNKRYQKTAA YGHFGRDDPD FTWETVKKLE 390 Gene Ontology GO:0005829; C: cytosol; IEA: EnsemblPlants/Gramene GO:0005886; C: plasma membrane; IEA: EnsemblPlants/Gramene GO:0009506; C: plasmodesma; IEA: EnsemblPlants/Gramene GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0005507; F: copper ion binding; IEA: EnsemblPlants/Gramene GO:0004478; F: methionine adenosyltransferase activity; IEA: UniProtKB-EC GO:0006730; P: one-carbon metabolic process; IEA: UniProtKB-KW GO:0006556; P: S-adenosylmethionine biosynthetic process; IEA: UniProtKB-UniPathway Interpro Pfam SMART PROSITE PRINTS |