※ dbPPT Protein Information
| Tag | Content | ||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt Accession | |||||||||||||||||||||||||||||||||||||||
Theoretical PI | 5.85 | ||||||||||||||||||||||||||||||||||||||
Molecular Weight | 70014.73 | ||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||
Protein Name | Cleavage and polyadenylation specificity factor CPSF30; Zinc finger CCCH domain-containing protein 11; AtC3H11 | ||||||||||||||||||||||||||||||||||||||
Gene Name | CPSF30; At1g30460; F26G16.5; F26G16.6 | ||||||||||||||||||||||||||||||||||||||
Created Date | 2009-05-05 | ||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Binds RNA in a calcium-dependent manner. Sequence Annotation chain 1 631 Cleavage and polyadenylation specificity factor CPSF30 domain 237 372 YTH zinc finger region 60 87 C3H1-type 1 zinc finger region 88 112 C3H1-type 2 zinc finger region 114 141 C3H1-type 3 compositionally biased region 142 147 Poly-Pro compositionally biased region 199 212 Poly-Gln compositionally biased region 417 431 Poly-Glu compositionally biased region 435 553 Gly-rich modified residue 610 Phosphoserine modified residue 612 Phosphoserine splice variant 239 250 In isoform 2. splice variant 251 631 In isoform 2. Keyword Alternative splicing,Complete proteome,DNA-binding,Metal-binding,mRNA processing,Nucleus,Phosphoprotein,Reference proteome,Repeat,RNA-binding,Zinc,Zinc-finger Sequence Source UniProt Protein Sequence MEDADGLSFD FEGGLDSGPV QNTASVPVAP PENSSSAAVN VAPTYDHSSA TVAGAGRGRS 60 FRQTVCRHWL RGLCMKGDAC GFLHQFDKAR MPICRFFRLY GECREQDCVY KHTNEDIKEC 120 NMYKLGFCPN GPDCRYRHAK LPGPPPPVEE VLQKIQQLTT YNYGTNRLYQ ARNVAPQLQD 180 RPQGQVPMQG QPQESGNLQQ QQQQQPQQSQ HQVSQTLIPN PADQTNRTSH PLPQGVNRYF 240 VVKSNNRENF ELSVQQGVWA TQRSNEAKLN EAFDSVENVI LIFSVNRTRH FQGCAKMTSR 300 IGGYIGGGNW KHEHGTAQYG RNFSVKWLKL CELSFHKTRN LRNPYNENLP VKISRDCQEL 360 EPSVGEQLAS LLYLEPDSEL MAISIAAEAK REEEKAKGVN PESRAENPDI VPFEDNEEEE 420 EEEDESEEEE ESMAGGPQGR GRGRGIMWPP QMPLGRGIRP MPGMGGFPLG VMGPGDAFPY 480 GPGGYNGMPD PFGMGPRPFG PYGPRFGGDF RGPVPGMMFP GRPPQQFPHG GYGMMGGGRG 540 PHMGGMGNAP RGGRPMYYPP ATSSARPGPS NRKTPERSDE RGVSGDQQNQ DASHDMEQFE 600 VGNSLRNEES ESEDEDEAPR RSRHGEGKKR R 631 Gene Ontology GO:0005847; C: mRNA cleavage and polyadenylation specificity factor complex; ISS: TAIR GO:0005634; C: nucleus; IDA: TAIR GO:0005516; F: calmodulin binding; IDA: TAIR GO:0003677; F: DNA binding; IEA: UniProtKB-KW GO:0004519; F: endonuclease activity; IDA: TAIR GO:0004521; F: endoribonuclease activity; IDA: TAIR GO:0046872; F: metal ion binding; IEA: UniProtKB-KW GO:0005515; F: protein binding; IPI: IntAct GO:0003723; F: RNA binding; IDA: TAIR GO:0006378; P: mRNA polyadenylation; IMP: TAIR GO:0090305; P: nucleic acid phosphodiester bond hydrolysis; IDA: GOC GO:1900363; P: regulation of mRNA polyadenylation; IMP: TAIR GO:0006979; P: response to oxidative stress; IMP: TAIR GO:0090502; P: RNA phosphodiester bond hydrolysis, endonucleolytic; IDA: GOC GO:0006396; P: RNA processing; IDA: TAIR Interpro Pfam Pfam; PF04146; YTH SMART SMART; SM00356; ZnF_C3H1 PROSITE PRINTS |