※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||
Theoretical PI | 8.2 | ||||||||||||||||||||||||||||||||||
Molecular Weight | 132646.81 | ||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||
Protein Name | DNA topoisomerase 2 | ||||||||||||||||||||||||||||||||||
Gene Name | PHYPADRAFT_134247 | ||||||||||||||||||||||||||||||||||
Created Date | 2008-02-05 | ||||||||||||||||||||||||||||||||||
Organism | Physcomitrella patens subsp. patens(Moss) | ||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3218 | ||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (By similarity). Sequence Annotation non-terminal residue 1 Keyword ATP-binding,Complete proteome,DNA-binding,Isomerase,Nucleotide-binding,Reference proteome,Topoisomerase Sequence Source UniProt Protein Sequence APKVAKLPLQ SSSGFNIDRE PQNDKSIEET YQKKTQLEHI LLRPDTYVGS IEKHTQSLWV 60 YEDEKMVNRS VTFVPGLYKI FDEILVNAAD NKQRDPSMDT VKVEIDVENN FISVFNNGDG 120 VPVEIHKEEG VYVPEMIFGH LLTSSNYNDS EKKTTGGRNG YGAKLANIFS TEFTIETADG 180 KRLRRYKQVF TNNMSLKSEP KITTCKANEN WTKVSFKPDL SKFNMTHLES DVVALMSKRV 240 MDVAGCLGKG CKVELNGKRL PIKSFQDYVG LYLSVANAGR EEPLPRIYER VSDRWEVCVS 300 LSDGQFNQVS FCNSIATIRG GTHVAYVTDQ IVTHVLALVN KKNKTAGVKP FQIKNHMWVF 360 VNALIDNPTF DSQTKETLTT RASSFGSKCE LSPEFLKKVA KCGVVENVLT WADFKQSKEL 420 KKNDGAKRQR ITGIPKLDDA NDAGGKSSEK CTLILTEGDS AKALAMSGIS VVGRDKYGVF 480 PLRGKLLNVR EASHKQIMEN AEITNIKRIL GLQHGKDYDS TKSLRYGHLM IMTDQDHDGS 540 HIKGLLINFI HSFWPSLLKI PSFLVEFITP IVKATNKQKT LSFYTMPEYE AWKESLNGET 600 KGWTIKYYKG LGTSTSKEGK EYFRELVKHK KDFKWESEMD GDAIEMAFSK KKIEARKTWL 660 RHYEPGTFLD MTAEKINYRD FVNKELILFS MADLARSIPS MVDGLKPGQR KILFCCFKRN 720 FVTQAKVAQF SGYVSEHSAY HHGEASLAST IIGMAQNFVG SNNINLLSPE GQFGTREQGG 780 KNHASPRYIF TCLAPITRAL FPQADDVLLD YLKEDGQSIE PTWYCPIIPL VLVNGSEGIG 840 TGWSSFVPNY NPREIVANLR RLLAGQEMEP MHPWYKGFKG SIECSATKDS GFTYTITGAI 900 DQIDETTIKI SELPVRKWTQ DYKEFLDVMM TPSDKNKEPF IKDFREHNTD TKVHFELSLS 960 EENMAIALAE GLVKKFKLTT TISTSNMHLF DNKGIIKKYD TPEQILEEFF HIRLDMYVKR 1020 KAVQLQNLEY ELHKVDNKVR FILGVVKGEI IVNNRKRADL LADLQKKGFT PFPKKSKSSD 1080 PPVVGADPLP EDDEQDEKVK GIRAADYEYL LSMPIGTLTF EKVQQLRGQR DKMEGEVEEL 1140 KKATPEALWI KDLDEFLVKL DVSNACILSC TI 1172 Gene Ontology GO:0005634; C: nucleus; IEA: EnsemblPlants/Gramene GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0003677; F: DNA binding; IEA: UniProtKB-KW GO:0003918; F: DNA topoisomerase type II (ATP-hydrolyzing) activity; IEA: UniProtKB-EC GO:0006265; P: DNA topological change; IEA: InterPro Interpro InterPro; IPR024946; Arg_repress_C-like InterPro; IPR003594; HATPase_ATP-bd InterPro; IPR020568; Ribosomal_S5_D2-typ_fold InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr InterPro; IPR001241; Topo_IIA InterPro; IPR002205; Topo_IIA_A/C InterPro; IPR013758; Topo_IIA_A/C_ab InterPro; IPR013757; Topo_IIA_A_a InterPro; IPR013506; Topo_IIA_bsu_dom2 InterPro; IPR013759; Topo_IIA_cen_dom InterPro; IPR013760; Topo_IIA_like_dom InterPro; IPR018522; TopoIIA_CS InterPro; IPR006171; Toprim_domain Pfam SMART PROSITE PRINTS PR00418; TPI2FAMILY |