※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 6.19 | ||||||||||||||||||||||||||||||
Molecular Weight | 61156.7 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Folylpolyglutamate synthase; Folylpoly-gamma-glutamate synthetase; Tetrahydrofolylpolyglutamate synthase | ||||||||||||||||||||||||||||||
Gene Name | SELMODRAFT_229276 | ||||||||||||||||||||||||||||||
Created Date | 2010-10-05 | ||||||||||||||||||||||||||||||
Organism | Selaginella moellendorffii(Spikemoss) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 88036 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis (By similarity). Sequence Annotation Keyword Complete proteome,Ligase,One-carbon metabolism Sequence Source UniProt Protein Sequence MSGHDRRSGA QGCAQSLAMA HRRSFRDAIE ILNGLITKKR GGGGAVVDLD RSPSTHDSSR 60 WENHFQLVAD HLKLLGLEEP VSKLSVIHVA GTKGKGSTCA FVERILRASG FRTALFTSPH 120 LLDIRERFRL NGEEVSEETF NKYFWWCWDH LQANEAEQGL PMPRLFRFLT ILAFKMFTSE 180 DVDVAILEVG LGGRCDATNV VRNPAICGVA SLGYDHMEIL GNTLAEIATE KAGIFKAGVP 240 AVTVPQPAEA LEALKKRALE LNIPLEIAPP LETYNLGDLK LGLQGEHQRT NAALAVRLCR 300 GWAERSDHQE HKAILNEALE QGRLPDSYIK GLVEVRWAGR AEIVREKKLS FYLDGAHSPE 360 SMEACAKWFS SAARADNIHK ENEEISAFDI KQFYTPTSNS RQILLFNCMP KRDPNLLFPP 420 LLDICKQQDI SLELAIFVPP YSSYTSIDNT HDSPVDPDLS WQKVLQQHWE SFKEKDSKAE 480 DYRREFLSGL ENGYSSCHFG VSSAVMPSLP AAIDWLRFCS ARHPNLHLQV LVTGSLYLVG 540 DVLRLLK 547 Gene Ontology GO:0005524; F: ATP binding; IEA: InterPro GO:0004326; F: tetrahydrofolylpolyglutamate synthase activity; IEA: UniProtKB-EC GO:0006730; P: one-carbon metabolic process; IEA: UniProtKB-KW Interpro Pfam Pfam; PF08245; Mur_ligase_M SMART PROSITE PRINTS |