※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
4.89 
Molecular Weight
27740.72 
Genbank Protein ID
 
Genbank Nucleotide ID
 
Protein Name
Anamorsin homolog; Fe-S cluster assembly protein DRE2 homolog 
Gene Name
BRADI5G25970 
Created Date
2012-06-13 
Organism
Brachypodium distachyon(Purple false brome Trachynia distachya) 
NCBI Taxa ID
15368 
Phosphorylation Sites
Position
Peptide
Source
References
256
LGEKVSLSDNFLSAD
dbPPT
[1]
254
FKLGEKVSLSDNFLS
dbPPT
[1]
Functional Description
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Has anti-apoptotic effects in the cell (By similarity). 
Sequence Annotation
region of interest 1 142 N-terminal domain
region of interest 145 173 Linker
region of interest 174 264 Intrinsically disordered
short sequence motif 225 228 Cx2C motif 1
short sequence motif 236 239 Cx2C motif 2
metal ion-binding site 185 Iron-sulfur (2Fe-2S)
metal ion-binding site 194 Iron-sulfur (2Fe-2S)
metal ion-binding site 197 Iron-sulfur (2Fe-2S)
metal ion-binding site 199 Iron-sulfur (2Fe-2S)
Keyword
2Fe-2S,Apoptosis,Complete proteome,Cytoplasm,Iron,Iron-sulfur,Metal-binding,Mitochondrion,Reference proteome 
Sequence Source
UniProt 
Protein Sequence
MAAAALAVTD ELALPLRAVG DLAAAAGISR EEVVVITQCA TLGGKLPFDD ASVGAVLSVI 60
KKAESFGDQL VAEVSRVLKA GGIVLVQSFT PSSEQKPNNY IERQLLMGGF VEVQTSATSS 120
QDSVQSVTIK AKKPSWSMGS SFPLKKATKA LPKIQIDDDD ELIDEDSLLT AEDLKKPQLP 180
VVGDCEVGAA KKACKNCTCG RAEAEQKVEK LELTAEQINN PVSSCGSCGL GDAFRCSTCP 240
YRGLAPFKLG EKVSLSDNFL SADI 264 
Gene Ontology
GO:0005758; C: mitochondrial intermembrane space; IEA: UniProtKB-SubCell
GO:0051537; F: 2 iron, 2 sulfur cluster binding; IEA: UniProtKB-HAMAP
GO:0009055; F: electron carrier activity; IEA: UniProtKB-HAMAP
GO:0046872; F: metal ion binding; IEA: UniProtKB-KW
GO:0006915; P: apoptotic process; IEA: UniProtKB-KW
GO:0016226; P: iron-sulfur cluster assembly; IEA: UniProtKB-HAMAP
GO:0043066; P: negative regulation of apoptotic process; IEA: UniProtKB-HAMAP 
Interpro
InterPro; IPR007785; Anamorsin
InterPro; IPR029063; SAM-dependent_MTases-like
Pfam
Pfam; PF05093; CIAPIN1 
SMART
 
PROSITE
 
PRINTS