※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||
Theoretical PI | 6.37 | ||||||||||||||||||||||||||||||||||
Molecular Weight | 77745.26 | ||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||
Protein Name | Delta-1-pyrroline-5-carboxylate synthase; P5CS; Glutamate 5-kinase; GK; Gamma-glutamyl kinase; Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase | ||||||||||||||||||||||||||||||||||
Gene Name | P5CS; Os05g0455500; LOC_Os05g38150; OJ1651_D06.9 | ||||||||||||||||||||||||||||||||||
Created Date | 2000-05-30 | ||||||||||||||||||||||||||||||||||
Organism | Oryza sativa subsp. japonica(Rice) | ||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 39947 | ||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants. Sequence Annotation chain 1 716 Delta-1-pyrroline-5-carboxylate synthase nucleotide phosphate-binding region 196 197 ATP nucleotide phosphate-binding region 236 242 ATP region of interest 1 296 Glutamate 5-kinase region of interest 297 716 Gamma-glutamyl phosphate reductase binding site 60 Substrate binding site 157 Substrate binding site 176 Substrate; via amide nitrogen Keyword Amino-acid biosynthesis,ATP-binding,Complete proteome,Kinase,Multifunctional enzyme,NADP,Nucleotide-binding,Oxidoreductase,Proline biosynthesis,Reference proteome,Transferase Sequence Source UniProt Protein Sequence MASVDPSRSF VRDVKRVIIK VGTAVVSRQD GRLALGRVGA LCEQVKELNS LGYEVILVTS 60 GAVGVGRQRL RYRKLVNSSF ADLQKPQMEL DGKACAAVGQ SGLMALYDML FNQLDVSSSQ 120 LLVTDSDFEN PKFREQLTET VESLLDLKVI PIFNENDAIS TRKAPYEDSS GIFWDNDSLA 180 GLLALELKAD LLILLSDVDG LYSGPPSEPS SKIIHTYIKE KHQQEITFGD KSRVGRGGMT 240 AKVKAAVLAS NSGTPVVITS GFENRSILKV LHGEKIGTLF HKNANLWESS KDVSTREMAV 300 AARDCSRHLQ NLSSEERKKI LLDVADALEA NEDLIRSENE ADVAAAQVAG YEKPLVARLT 360 IKPGKIASLA KSIRTLANME DPINQILKKT EVADDLVLEK TSCPLGVLLI VFESRPDALV 420 QIASLAIRSG NGLLLKGGKE AIRSNTILHK VITDAIPRNV GEKLIGLVTT RDEIADLLKL 480 DDVIDLVIPR GSNKLVSQIK ASTKIPVLGH ADGICHVYID KSADMDMAKH IVMDAKIDYP 540 AACNAMETLL VHKDLMKSPG LDDILVALKT EGVNIYGGPI AHKALGFPKA VSFHHEYSSM 600 ACTVEFVDDV QSAIDHIHRY GSAHTDCIVT TDDKVAETFL RRVDSAAVFH NASTRFSDGA 660 RFGLGAEVGI STGRIHARGP VGVEGLLTTR WILRGRGQVV NGDKDVVYTH KSLPLQ 716 Gene Ontology GO:0009507; C: chloroplast; IEA: EnsemblPlants/Gramene GO:0005829; C: cytosol; IEA: EnsemblPlants/Gramene GO:0009506; C: plasmodesma; IEA: EnsemblPlants/Gramene GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0004349; F: glutamate 5-kinase activity; IEA: UniProtKB-EC GO:0004350; F: glutamate-5-semialdehyde dehydrogenase activity; IEA: UniProtKB-EC GO:0009793; P: embryo development ending in seed dormancy; IEA: EnsemblPlants/Gramene GO:0055129; P: L-proline biosynthetic process; IEA: UniProtKB-UniPathway GO:0009555; P: pollen development; IEA: EnsemblPlants/Gramene Interpro InterPro; IPR016161; Ald_DH/histidinol_DH InterPro; IPR016163; Ald_DH_C InterPro; IPR016162; Ald_DH_N InterPro; IPR015590; Aldehyde_DH_dom InterPro; IPR001048; Asp/Glu/Uridylate_kinase InterPro; IPR000965; G-glutamylP_reductase InterPro; IPR020593; G-glutamylP_reductase_CS InterPro; IPR001057; Glu/AcGlu_kinase InterPro; IPR005715; Glu_5kinase/COase_Synthase InterPro; IPR019797; Glutamate_5-kinase_CS InterPro; IPR005766; P5_carboxy_syn Pfam SMART PROSITE PRINTS PR00474; GLU5KINASE |