※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.92 
Molecular Weight
53055.62 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
6-phosphogluconate dehydrogenase, decarboxylating 
Gene Name
pdh1 
Created Date
1998-11-01 
Organism
Zea mays(Maize) 
NCBI Taxa ID
4577 
Phosphorylation Sites
Position
Peptide
Source
References
108
VDGGNEWYENTERRE
dbPPT
[1]
89
PVDQTIATLAAHLDQ
dbPPT
[1]
Functional Description
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity). 
Sequence Annotation
nucleotide phosphate-binding region 10 15 NADP
nucleotide phosphate-binding region 33 35 NADP
nucleotide phosphate-binding region 77 79 NADP
region of interest 131 133 Substrate binding
region of interest 189 190 Substrate binding
active site 186 Proton acceptor
active site 193 Proton donor
binding site 105 NADP
binding site 105 Substrate
binding site 194 Substrate
binding site 264 Substrate; via amide nitrogen
binding site 291 Substrate
binding site 450 Substrate; shared with dimeric partner
binding site 456 Substrate; shared with dimeric partner
Keyword
NADP,Oxidoreductase,Pentose shunt 
Sequence Source
UniProt 
Protein Sequence
MALTRIGLAG LAVMGQNLAL NIAEKGFPIS VYNRTTSKVD ETVQRAKVEG NLPVFGFHDP 60
ASFVSSIQKP RVVIMLVKAG APVDQTIATL AAHLDQGDCI VDGGNEWYEN TERREKAMEE 120
RGLLYLGMGV SGGEEGARNG PSLMPGGSFE AYKYIEDILL KVAAQVPDSG PCVTYIGKGG 180
SGNFVKMVHN GIEYGDMQLI AEAYDVLKSV GKLTNSELHQ VFSEWNKGEL LSFLIEITAD 240
IFGIKDDKGE GYLVDKVLDK TGMKGTGKWT VQQAAELSVA APTIEASLDS RFLSGLKDER 300
VEASKIFQGD YSTGLPVDKA QLIEDVRQAL YASKICSYAQ GMNIIKAKSS EKGWGLNLGE 360
LARIWKGGCI IRAIFLDRIK KAYDRNPNLA NLLVDPEFAQ EIIDRQAAWR RVVCLAINNG 420
VSTPGMSASL AYFDSYRRDR LPANLVQAQR DYFGAHTYER VDMPVLSTPR LRETTSALTR 480
YEKV 484 
Gene Ontology
GO:0009570; C: chloroplast stroma; IEA: EnsemblPlants/Gramene
GO:0005829; C: cytosol; IEA: EnsemblPlants/Gramene
GO:0005777; C: peroxisome; IEA: EnsemblPlants/Gramene
GO:0050661; F: NADP binding; IEA: InterPro
GO:0004616; F: phosphogluconate dehydrogenase (decarboxylating) activity; IEA: UniProtKB-EC
GO:0006098; P: pentose-phosphate shunt; IEA: UniProtKB-UniPathway
GO:0009651; P: response to salt stress; IEA: EnsemblPlants/Gramene 
Interpro
InterPro; IPR008927; 6-PGluconate_DH_C-like
InterPro; IPR006114; 6PGDH_C
InterPro; IPR006113; 6PGDH_decarbox
InterPro; IPR006115; 6PGDH_NADP-bd
InterPro; IPR013328; DH_multihelical
InterPro; IPR012284; Fibritin/6PGD_C-extension
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF00393; 6PGD
Pfam; PF03446; NAD_binding_2 
SMART
 
PROSITE
 
PRINTS