※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
6.24 
Molecular Weight
52952.44 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
6-phosphogluconate dehydrogenase, decarboxylating 
Gene Name
pdh2 
Created Date
1998-11-01 
Organism
Zea mays(Maize) 
NCBI Taxa ID
4577 
Phosphorylation Sites
Position
Peptide
Source
References
316
GDYYSTGSPVDKAQL
dbPPT
[1]
Functional Description
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity). 
Sequence Annotation
nucleotide phosphate-binding region 10 15 NADP
nucleotide phosphate-binding region 33 35 NADP
nucleotide phosphate-binding region 77 79 NADP
region of interest 131 133 Substrate binding
region of interest 189 190 Substrate binding
active site 186 Proton acceptor
active site 193 Proton donor
binding site 105 NADP
binding site 105 Substrate
binding site 194 Substrate
binding site 264 Substrate; via amide nitrogen
binding site 291 Substrate
binding site 451 Substrate; shared with dimeric partner
binding site 457 Substrate; shared with dimeric partner
Keyword
NADP,Oxidoreductase,Pentose shunt 
Sequence Source
UniProt 
Protein Sequence
MALTRIGLAG LAVMGQNLAL NIAEKGFPIS VYNRTTSKVD ETVQRAKAEG NLPVYGFHDP 60
ASFVKSIQKP RVVIMLVKAG APVDQTIATL AAHLEQGDCI IDGGNEWYEN TERREKAMEE 120
RGLLYLGMVV SGGEEGARNG PSLMPGGSFE AYKYVKDIVL KVAAQVPDSG PCVTYIGKGG 180
SGNFVKMVHN GIEYGDMQLI SEAYDVLKFV GKLTNSELHQ VFSEWNKGEL LSFLIEITAD 240
IFGIKDEHGD GYLVDKVLDK TGMKGTGKWT VQQAAELSVA APTIEASLDS RFLSGLKDER 300
VEASKIFQGD YYSTGSPVDK AQLVEDVRQA LYASKICSYA QGMNIIKAKS AEKGWGLNLG 360
ELARIWKGGC IIRAIFLDRI KKAYDRNPGL ASLLVDPEFA QEIMDRQAAW RRVVCLAINN 420
GVSTPGMSAS LAYFDSYRRD RLPANLVQAQ RDYFGAHTYE RVDMPGSFHT EWFKIARNIS 480
NN 482 
Gene Ontology
GO:0050661; F: NADP binding; IEA: InterPro
GO:0004616; F: phosphogluconate dehydrogenase (decarboxylating) activity; IEA: UniProtKB-EC
GO:0006098; P: pentose-phosphate shunt; IEA: UniProtKB-UniPathway 
Interpro
InterPro; IPR008927; 6-PGluconate_DH_C-like
InterPro; IPR006114; 6PGDH_C
InterPro; IPR006113; 6PGDH_decarbox
InterPro; IPR006115; 6PGDH_NADP-bd
InterPro; IPR013328; DH_multihelical
InterPro; IPR012284; Fibritin/6PGD_C-extension
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF00393; 6PGD
Pfam; PF03446; NAD_binding_2 
SMART
 
PROSITE
 
PRINTS