※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 8.88 | ||||||||||||||||||||||||||||||
Molecular Weight | 78039.94 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Plasma membrane ATPase 2; Proton pump 2 | ||||||||||||||||||||||||||||||
Gene Name | LHA2 | ||||||||||||||||||||||||||||||
Created Date | 1992-03-01 | ||||||||||||||||||||||||||||||
Organism | Solanum lycopersicum(Tomato Lycopersicon esculentum) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 4081 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Sequence Annotation chain 1 704 Plasma membrane ATPase 2 transmembrane region 1 16 Helical; Name=3; topological domain 17 26 Extracellular transmembrane region 27 48 Helical; Name=4; topological domain 49 395 Cytoplasmic transmembrane region 396 417 Helical; Name=5; topological domain 418 422 Extracellular transmembrane region 423 445 Helical; Name=6; topological domain 446 461 Cytoplasmic transmembrane region 462 482 Helical; Name=7; topological domain 483 507 Extracellular transmembrane region 508 528 Helical; Name=8; topological domain 529 540 Cytoplasmic transmembrane region 541 561 Helical; Name=9; topological domain 562 570 Extracellular transmembrane region 571 591 Helical; Name=10; topological domain 592 704 Cytoplasmic active site 81 4-aspartylphosphate intermediate metal ion-binding site 340 Magnesium metal ion-binding site 344 Magnesium non-terminal residue 1 Keyword ATP-binding,Cell membrane,Complete proteome,Hydrogen ion transport,Hydrolase,Ion transport,Magnesium,Membrane,Metal-binding,Nucleotide-binding,Phosphoprotein,Reference proteome,Transmembrane,Transmembrane helix,Transport Sequence Source UniProt Protein Sequence CSIAVGMIIE IIVMYPIQHR KYRPGIDNLL VLLIGGIPIA MPTVLSVTMA IGSHRLAQQG 60 AITKRMTAIE EMAGMDVLCS DKTGTLTLNK LTVDKNLVEV FAKGVDADTV VLMAARASRT 120 ENQDAIDTAI VGMLADPKEA RAGIREIHFL PFNPTDKRTA LTYLDGEGKM HRVSKGAPEQ 180 ILNLAHNKSD IERRVHTVID KFAERGLRSL GVAYQEVPEG RKESSGGPWQ FIGLLPLFDP 240 PRHDSAETIR RALNLGVNVK MITGDQLAIG KETGRRLGMG TNMYPSSALL GQTKDESIAS 300 LPIDELIEKA DGFAGVFPEH KYEIVKRLQA RKHICGMTGD GVNDAPALKK ADIGIAVDDA 360 TDAARSASDI VLTEPGLSVI ISAVLTSRAI FQRMKNYTIY AVSITIRIVL GFMLLALIWK 420 FDFPPFMVLI IAILNDGTIM TISKDRVKPS PLPDSWKLAE IFTTGVVLGG YLAMMTVIFF 480 WAAYETQFFP RVFGVSTLQR TATDDFRKLA SAIYLQVSTI SQALIFVTRS RSWSFVERPG 540 LLLVVALIVA QLVATLIAVY ASWSFAAIEG IGWGWAGVIW LYNLVFYFPL DIIKFLIRYA 600 LSGRAWDLVL EQRIAFTRKK DFGKEQRELQ WAHAQRTLHG LQVPDIKLFS EATNFNELNQ 660 LAEEAKRRAE IARQRELHTL KGHVESVVKL KGLDIETIQQ SYTV 704 Gene Ontology GO:0016021; C: integral component of membrane; IEA: UniProtKB-KW GO:0005886; C: plasma membrane; IEA: UniProtKB-SubCell GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0008553; F: hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA: UniProtKB-EC GO:0046872; F: metal ion binding; IEA: UniProtKB-KW GO:0006754; P: ATP biosynthetic process; IEA: InterPro Interpro Pfam SMART PROSITE PS00154; ATPASE_E1_E2 PRINTS PR00119; CATATPASE PR00120; HATPASE |