※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
7.06 
Molecular Weight
100335.74 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic; AK-HD 1; AK-HSDH 1; Aspartokinase; Homoserine dehydrogenase 
Gene Name
AKHSDH1 
Created Date
1996-02-01 
Organism
Zea mays(Maize) 
NCBI Taxa ID
4577 
Phosphorylation Sites
Position
Peptide
Source
References
467
EKEVALVSAALHARF
dbPPT
[1]
Functional Description
 
Sequence Annotation
transit peptide 1 92 Chloroplast
chain 93 920 Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic
domain 416 491 ACT 1
domain 497 574 ACT 2
nucleotide phosphate-binding region 568 573 NADP
region of interest 93 341 Aspartokinase
region of interest 342 566 Interface
region of interest 567 920 Homoserine dehydrogenase
Keyword
Amino-acid biosynthesis,ATP-binding,Chloroplast,Complete proteome,Kinase,Methionine biosynthesis,Multifunctional enzyme,NADP,Nucleotide-binding,Oxidoreductase,Plastid,Reference proteome,Repeat,Transferase,Transit peptide 
Sequence Source
UniProt 
Protein Sequence
MRSLTVASRH PGAAFSTRRR PLLHPAAAGR DSTFQRCWRW EKTQDSSFGS SLRTSRLPRT 60
VHGDILKNLL APTAGAVSVE QAEAIADLPK GDMWSVHKFG GTCMGTSERI HNVADIVLRD 120
PSERKLVVVS AMSKVTDMMY NLVNKAQSRD DSYIAVLDEV FDKHMTTAKD LLAGEDLARF 180
LSQLHADISN LKAMLRAIYI AGHATESFSD FVVGHGELWS AQMLSYAIQK SGTPCSWMDT 240
REVLVVNPSG ANQVDPDYLE SEKRLEKWFS RCPAETIIAT GFIASTPENI PTTLKRDGSD 300
FSAAIIGSLV KARQVTIWTD VDGVFSADPR KVSEAVILST LSYQEAWEMS YFGANVLHPR 360
TIIPVMKYNI PIVIRNIFNT SAPGTMICQQ PANENGDLEA CVKAFATIDK LALVNVEGTG 420
MAGVPGTANA IFGAVKDVGA NVIMISQASS EHSVCFAVPE KEVALVSAAL HARFREALAA 480
GRLSKVEVIH NCSILATVGL RMASTPGVSA TLFDALAKAN INVRAIAQGC SEYNITIVLK 540
QEDCVRALRA AHSRFFLSKT TLAVGIIGPG LIGRTLLNQL KDQAAVLKEN MNIDLRVMGI 600
AGSRTMLLSD IGVDLTQWKE KLQTEAEPAN LDKFVHHLSE NHFFPNRVLV DCTADTSVAS 660
HYYDWLKKGI HVITPNKKAN SGPLDRYLKL RTLQRASYTH YFYEATVGAG LPIISTLRGL 720
LETGDKILRI EGIFSGTLSY IFNNFEGART FSDVVAEAKK AGYTEPDPRD DLSGTDVARK 780
VIILARESGL GLELSDIPVR SLVPEALKSC TSADEYMQKL PSFDEDWARE RKNAEAAGEV 840
LRYVGVVDVV SKKGQVELRA YKRDHPFAQL SGSDNIIAFT TSRYKDQPLI VRGPGAGAEV 900
TAGGVFCDIL RLSSYLGAPS 920 
Gene Ontology
GO:0009507; C: chloroplast; IEA: UniProtKB-SubCell
GO:0016597; F: amino acid binding; IEA: InterPro
GO:0004072; F: aspartate kinase activity; IEA: UniProtKB-EC
GO:0005524; F: ATP binding; IEA: UniProtKB-KW
GO:0004412; F: homoserine dehydrogenase activity; IEA: UniProtKB-EC
GO:0050661; F: NADP binding; IEA: InterPro
GO:0009089; P: lysine biosynthetic process via diaminopimelate; IEA: UniProtKB-UniPathway
GO:0009086; P: methionine biosynthetic process; IEA: UniProtKB-KW
GO:0009088; P: threonine biosynthetic process; IEA: UniProtKB-UniPathway 
Interpro
InterPro; IPR002912; ACT_dom
InterPro; IPR001048; Asp/Glu/Uridylate_kinase
InterPro; IPR005106; Asp/hSer_DH_NAD-bd
InterPro; IPR001341; Asp_kinase_dom
InterPro; IPR018042; Aspartate_kinase_CS
InterPro; IPR001342; HDH_cat
InterPro; IPR019811; HDH_CS
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF00696; AA_kinase
Pfam; PF01842; ACT
Pfam; PF00742; Homoserine_dh
Pfam; PF03447; NAD_binding_3 
SMART
 
PROSITE
PS51671; ACT
PS00324; ASPARTOKINASE
PS01042; HOMOSER_DHGENASE 
PRINTS