※ dbPPT Protein Information
| Tag | Content | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 6.38 | ||||||||||||||||||||||||||||||
Molecular Weight | 40434 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; PDHE1-A | ||||||||||||||||||||||||||||||
Gene Name | |||||||||||||||||||||||||||||||
Created Date | 1996-10-01 | ||||||||||||||||||||||||||||||
Organism | Solanum tuberosum(Potato) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 4113 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Sequence Annotation transit peptide 1 26 Mitochondrion chain 27 391 Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial Keyword Complete proteome,Direct protein sequencing,Glycolysis,Mitochondrion,Oxidoreductase,Phosphoprotein,Pyruvate,Reference proteome,Thiamine pyrophosphate,Transit peptide Sequence Source UniProt Protein Sequence MALSTSRAIN HIMKPLSAAV CATRRLSSDS TATITVETSL PFTSHNIDPP SRSVETSPKE 60 LMTFFKDMTE MRRMEIAADS LYKAKLIRGF CHLYDGQEAV AVGMEAAITK KDCIITAYRD 120 HCIFLGRGGT LVEAFAELMG RRDGCSRGKG GSMHFYKKES GFYGGHGIVG AQVPLGIGLA 180 FAQKYKKEDY VTFAMYGDGA ANQGQLFEAL NMAALWDLPA ILVCENNHYG MGTAEWRAAK 240 SPAYYKRGDY VPGLRVDGMD VFAVKQACTF AKQHALKNGP IILEMDTYRY HGHSMSDPGS 300 TYRTRDEISG VRQERDPVER IRSLILAHNI ATEAELKDIE KENRKVVDEA IAKAKESPMP 360 DPSELFTNVY VKGFGVEAYG ADRKELRATL P 391 Gene Ontology GO:0005829; C: cytosol; IEA: EnsemblPlants/Gramene GO:0005759; C: mitochondrial matrix; IEA: UniProtKB-SubCell GO:0005634; C: nucleus; IEA: EnsemblPlants/Gramene GO:0050897; F: cobalt ion binding; IEA: EnsemblPlants/Gramene GO:0004739; F: pyruvate dehydrogenase (acetyl-transferring) activity; IEA: UniProtKB-EC GO:0008270; F: zinc ion binding; IEA: EnsemblPlants/Gramene GO:0006096; P: glycolytic process; IEA: UniProtKB-KW GO:0009651; P: response to salt stress; IEA: EnsemblPlants/Gramene Interpro Pfam Pfam; PF00676; E1_dh SMART PROSITE PRINTS |