※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||
Theoretical PI | 5.49 | ||||||||||||||||||||||||||||||||||
Molecular Weight | 57546.25 | ||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||
Protein Name | Probable histone deacetylase 19; RPD3 homolog | ||||||||||||||||||||||||||||||||||
Gene Name | |||||||||||||||||||||||||||||||||||
Created Date | 1998-07-15 | ||||||||||||||||||||||||||||||||||
Organism | Zea mays(Maize) | ||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 4577 | ||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Sequence Annotation chain 1 513 Probable histone deacetylase 19 region of interest 23 334 Histone deacetylase active site 154 Keyword Chromatin regulator,Complete proteome,Hydrolase,Nucleus,Reference proteome,Repressor,Transcription,Transcription regulation Sequence Source UniProt Protein Sequence MDPSSAGSGG NSLPSVGPDG QKRRVCYFYD PDVGNYYYGQ GHPMKPHRIR MTHSLLARYG 60 LLNQMQVYRP NPARERELCR FHAEEYINFL RSVTPETQQD QIRLLKRFNV GEECPVLDGL 120 YSFCQTYAGA SVGGAVKFNH GHDIAINWSG GLHHAKKCEA SGFCYVNDIV LAILELLKHH 180 ERVLYVDIDI HHGDGVEEAF YTTDRVMTVS FHKFGDYFPG TGDIRDIGHS KGKYYSLNVP 240 LDDGIDDESY QSLFKPIMGK VMEVFRPGAV VLQCGADSLS GDRLGCFNLS IKGHAECVRY 300 MRSFNVPLLL LGGGGYTIRN VARCWCYETG VALGQEPEDK MPVNEYYEYF GPDYTLHVAP 360 SNMENKNTRQ QLDDIRSKLS KLRHAPSVHF QERVPDTEIP EQDEDQDDPD ERHDPDSDME 420 VDDHKAVEES SRRSILGIKI KREFGENATR VQDGGRVASE HRGLEPMAED IGSSKQAPQA 480 DASAMAIDEP SNVKNEPESS TKLQGQAAAY HKP 513 Gene Ontology GO:0005634; C: nucleus; IEA: UniProtKB-SubCell GO:0032041; F: NAD-dependent histone deacetylase activity (H3-K14 specific); IEA: UniProtKB-EC GO:0097372; F: NAD-dependent histone deacetylase activity (H3-K18 specific); IEA: UniProtKB-EC GO:0046969; F: NAD-dependent histone deacetylase activity (H3-K9 specific); IEA: UniProtKB-EC GO:0046970; F: NAD-dependent histone deacetylase activity (H4-K16 specific); IEA: UniProtKB-EC GO:0009294; P: DNA mediated transformation; IEA: EnsemblPlants/Gramene GO:0016573; P: histone acetylation; IEA: EnsemblPlants/Gramene GO:0009861; P: jasmonic acid and ethylene-dependent systemic resistance; IEA: EnsemblPlants/Gramene GO:0045892; P: negative regulation of transcription, DNA-templated; IEA: EnsemblPlants/Gramene GO:0009405; P: pathogenesis; IEA: EnsemblPlants/Gramene GO:2000026; P: regulation of multicellular organismal development; IEA: EnsemblPlants/Gramene GO:0006351; P: transcription, DNA-templated; IEA: UniProtKB-KW Interpro Pfam Pfam; PF00850; Hist_deacetyl SMART PROSITE PRINTS PR01270; HDASUPER PR01271; HISDACETLASE |