※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
4.93 
Molecular Weight
82524.12 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Eukaryotic translation initiation factor 3 subunit B; eIF3b; eIF-3-eta; eIF3 p110 
Gene Name
TIF3B1; PRT1 
Created Date
2000-05-30 
Organism
Nicotiana tabacum(Common tobacco) 
NCBI Taxa ID
4097 
Phosphorylation Sites
Position
Peptide
Source
References
688
KLRDGEASDEEEEYE
dbPPT, P3DB
[1, 2]
Functional Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. 
Sequence Annotation
chain 1 719 Eukaryotic translation initiation factor 3 subunit B
domain 60 147 RRM
repeat 167 207 WD 1
repeat 511 553 WD 2
repeat 555 598 WD 3
compositionally biased region 619 716 Glu-rich
Keyword
Cytoplasm,Initiation factor,Protein biosynthesis,Repeat,RNA-binding,WD repeat 
Sequence Source
UniProt 
Protein Sequence
MADVTSMGEI TAIAARIGVD LSQIDLDSIH LPPGEDCGIP SDDDDLMEED PLEFDAGFGN 60
ILVVDNLPVV PKEKFEKLEG VVRKIYSQLG VIKEDGLWMP VDPETHKTLG YCFIEYNTPQ 120
EAELSKEKTH GYKLDRSHIF AVNMFDDIER FLKVPDEWAP PEIKPYVPGE NLQQWLTDEK 180
ARDQFVIRAG NDTEVLWNDA RQLKPELVYK RSFWTESFVQ WSPLGTYLAT VHRQGGAIWG 240
GATTSNRLMR YAHPQVKLID FSLAERYLVT YSSHEPSNPR DSHAVVLNIS DVRTGKVMRD 300
FQGSADEFAV GGTGGVTGVS WPVFRWSGGK QDKYFARIGK NVISVYETET FSLIDKKSIK 360
VENVMDFSWS PADPILALFV PECGNQPARV SLVQIPSKEE LRQKNLFSVS DCKMYWQSNG 420
DYLAVKVDRY TKTKKSTYTG FELFRIKERD IPIEVLELDN TNDKIPAFGW GPEGSPICCY 480
PSVTTPRPDI RFYSVPVWAL TPGLVSKLTT LKGKQANALY WSPGGRFLIL TGLKGFNGQL 540
EFFDVDELET MASAEHFMAT DVEWDPTGRY VATSVTSVHE MENGFNIWSF NGKLLYRILK 600
DHFFQYLWRP RPPSFLSKEK EEEIAKNLKR YSKKYEAEDQ DVSLQLSEQD REKRKKLKEE 660
WEAWINEWKR LHEEEKMERQ KLRDGEASDE EEEYEAKEVE VEEIINVTEE IIPFEESQQ 719 
Gene Ontology
GO:0016282; C: eukaryotic 43S preinitiation complex; IEA: UniProtKB-HAMAP
GO:0033290; C: eukaryotic 48S preinitiation complex; IEA: UniProtKB-HAMAP
GO:0005852; C: eukaryotic translation initiation factor 3 complex; IEA: UniProtKB-HAMAP
GO:0000166; F: nucleotide binding; IEA: InterPro
GO:0003743; F: translation initiation factor activity; IEA: UniProtKB-HAMAP
GO:0001731; P: formation of translation preinitiation complex; IEA: UniProtKB-HAMAP
GO:0006446; P: regulation of translational initiation; IEA: UniProtKB-HAMAP 
Interpro
InterPro; IPR011042; 6-blade_b-propeller_TolB-like
InterPro; IPR011400; EIF3B
InterPro; IPR012677; Nucleotide-bd_a/b_plait
InterPro; IPR000504; RRM_dom
InterPro; IPR013979; TIF_beta_prop-like
InterPro; IPR015943; WD40/YVTN_repeat-like_dom
Pfam
Pfam; PF08662; eIF2A
Pfam; PF00076; RRM_1 
SMART
SMART; SM00360; RRM 
PROSITE
PS50102; RRM 
PRINTS