※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.61 
Molecular Weight
17496.65 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Eukaryotic translation initiation factor 5A; eIF-5A; eIF-4D 
Gene Name
TIF5A 
Created Date
1996-10-01 
Organism
Zea mays(Maize) 
NCBI Taxa ID
4577 
Phosphorylation Sites
Position
Peptide
Source
References
2
******MSDSEEHHF
dbPPT, P3DB
[1, 2]
4
****MSDSEEHHFES
dbPPT, P3DB
[1, 2]
Functional Description
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond. 
Sequence Annotation
chain 1 160 Eukaryotic translation initiation factor 5A
modified residue 53 Hypusine
Keyword
Complete proteome,Direct protein sequencing,Hypusine,Initiation factor,Protein biosynthesis,Reference proteome 
Sequence Source
UniProt 
Protein Sequence
MSDSEEHHFE SKADAGASKT YPQQAGTVRK NGFIVIKNRP CKVVEVSTSK TGKHGHAKCH 60
FVAIDIFNGK KLEDIVPSSH NCDIPHVNRT EYQLIDISED GFVSLLTSDG NTKDDLRLPT 120
DETLVAQIKE GFESGKDLVV TVQSAMGEEQ ICALKDVGPK 160 
Gene Ontology
GO:0005634; C: nucleus; IEA: EnsemblPlants/Gramene
GO:0043022; F: ribosome binding; IEA: InterPro
GO:0003746; F: translation elongation factor activity; IEA: InterPro
GO:0003743; F: translation initiation factor activity; IEA: UniProtKB-KW
GO:0042742; P: defense response to bacterium; IEA: EnsemblPlants/Gramene
GO:0034050; P: host programmed cell death induced by symbiont; IEA: EnsemblPlants/Gramene
GO:0008612; P: peptidyl-lysine modification to peptidyl-hypusine; IEA: InterPro
GO:0045901; P: positive regulation of translational elongation; IEA: InterPro
GO:0045905; P: positive regulation of translational termination; IEA: InterPro
GO:0046686; P: response to cadmium ion; IEA: EnsemblPlants/Gramene
GO:0009611; P: response to wounding; IEA: EnsemblPlants/Gramene
GO:0006452; P: translational frameshifting; IEA: InterPro 
Interpro
InterPro; IPR012340; NA-bd_OB-fold
InterPro; IPR014722; Rib_L2_dom2
InterPro; IPR019769; Trans_elong_IF5A_hypusine_site
InterPro; IPR001884; Transl_elong_IF5A
InterPro; IPR020189; Transl_elong_IF5A_C
InterPro; IPR008991; Translation_prot_SH3-like
Pfam
Pfam; PF01287; eIF-5a 
SMART
 
PROSITE
PS00302; IF5A_HYPUSINE 
PRINTS