※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
6.34 
Molecular Weight
39415.17 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Formate dehydrogenase, mitochondrial; NAD-dependent formate dehydrogenase; FDH 
Gene Name
FDH1 
Created Date
1995-02-01 
Organism
Solanum tuberosum(Potato) 
NCBI Taxa ID
4113 
Phosphorylation Sites
Position
Peptide
Source
References
76
KGHQYIVTPDKEGPD
dbPPT, P3DB
[1, 2]
333
YMPNQAMTPHISGTT
dbPPT, P3DB
[1, 2]
Functional Description
Involved in formate-dependent oxygen uptake coupled to ATP synthesis. 
Sequence Annotation
transit peptide 1 25 Mitochondrion
chain 26 381 Formate dehydrogenase, mitochondrial
nucleotide phosphate-binding region 204 205 NAD
nucleotide phosphate-binding region 285 287 NAD
nucleotide phosphate-binding region 335 338 NAD
active site 287
active site 335 Proton donor
binding site 258 NAD; via carbonyl oxygen
binding site 311 NAD
Keyword
Complete proteome,Direct protein sequencing,Mitochondrion,NAD,Oxidoreductase,Reference proteome,Transit peptide 
Sequence Source
UniProt 
Protein Sequence
MAMSRVASTA ARAITSPSSL VFTRELQASP GPKKIVGVFY KANEYAEMNP NFLGCAENAL 60
GIREWLESKG HQYIVTPDKE GPDCELEKHI PDLHVLISTP FHPAYVTAER IKKAKNLQLL 120
LTAGIGSDHV DLKAAAAAGL TVAEVTGSNT VSVAEDELMR ILILVRNFLP GHHQVINGEW 180
NVAAIAHRAY DLEGKTVGTV GAGRIGRLLL QRLKPFNCNL LYHDRLKMDS ELENQIGAKF 240
EEDLDKMLSK CDIVVINTPL TEKTKGMFDK ERIAKLKKGV LIVNNARGAI MDTQAVVDAC 300
NSGHIAGYSG DVWYPQPAPK DHPWRYMPNQ AMTPHISGTT IDAQLRYAAG TKDMLDRYFK 360
GEDFPAENYI VKDGELAPQY R 381 
Gene Ontology
GO:0009507; C: chloroplast; IEA: EnsemblPlants/Gramene
GO:0005739; C: mitochondrion; IEA: UniProtKB-SubCell
GO:0009579; C: thylakoid; IEA: EnsemblPlants/Gramene
GO:0008863; F: formate dehydrogenase (NAD+) activity; IEA: UniProtKB-EC
GO:0051287; F: NAD binding; IEA: InterPro
GO:0016616; F: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA: InterPro
GO:0046686; P: response to cadmium ion; IEA: EnsemblPlants/Gramene 
Interpro
InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom
InterPro; IPR006140; D-isomer_2_OHA_DH_NAD-bd
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF00389; 2-Hacid_dh
Pfam; PF02826; 2-Hacid_dh_C 
SMART
 
PROSITE
PS00065; D_2_HYDROXYACID_DH_1
PS00670; D_2_HYDROXYACID_DH_2
PS00671; D_2_HYDROXYACID_DH_3 
PRINTS