※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 6.19 | ||||||||||||||||||||||||||||||
Molecular Weight | 512846.3 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Dynein gamma chain, flagellar outer arm | ||||||||||||||||||||||||||||||
Gene Name | ODA2; ODA-2 | ||||||||||||||||||||||||||||||
Created Date | 1997-11-01 | ||||||||||||||||||||||||||||||
Organism | Chlamydomonas reinhardtii(Chlamydomonas smithii) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 3055 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Force generating protein of eukaryotic cilia and flagella. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Sequence Annotation chain 1 4485 Dynein gamma chain, flagellar outer arm nucleotide phosphate-binding region 1819 1826 ATP nucleotide phosphate-binding region 2099 2106 ATP nucleotide phosphate-binding region 2425 2432 ATP nucleotide phosphate-binding region 2802 2809 ATP region of interest 1 1780 Stem region of interest 1781 2002 AAA 1 region of interest 2061 2279 AAA 2 region of interest 2384 2638 AAA 3 region of interest 2763 3013 AAA 4 region of interest 3077 3343 Stalk region of interest 3412 3643 AAA 5 region of interest 3857 4071 AAA 6 coiled-coil region 449 469 coiled-coil region 804 838 coiled-coil region 1093 1114 coiled-coil region 1275 1297 coiled-coil region 1699 1727 coiled-coil region 3077 3099 coiled-coil region 3196 3227 coiled-coil region 3265 3343 coiled-coil region 3569 3663 Keyword ATP-binding,Cell projection,Cilium,Cilium biogenesis/degradation,Coiled coil,Cytoplasm,Cytoskeleton,Direct protein sequencing,Dynein,Flagellum,Microtubule,Motor protein,Nucleotide-binding,Repeat Sequence Source UniProt Protein Sequence MALDNRHRLI VGKLAEAFGL PENVIEKTLT QDKQAVNSFF TPAGPPSLVF VYQVKEDKLK 60 DGSVGPVDNK PTLHRIGPHE RIHNSVYFTR LNPKGINEKT LEADMGSGEL SVLWALENFK 120 AIVSDLYLPI MQEQQQWGKM STEYLEDFLS STAKFGSMLT EAVATVSGGV EPMPDPRYID 180 QYGDLRPAGI TQAAGDDDTL QEMEECLTEW CREAELLLNQ TNKIKDGEER GPDTELEYWR 240 TRMSNFNSIT EHLKTKECKL VLGICSHAKT KAYLRWRGLD VQITDAANES KDNVKYLATL 300 EKSMEPMYQG RVTDITESLP ALMTNVRMMY TIARFYSTAE HMTRLFTKIT NQLVRRCKEQ 360 IMENGKIWDQ DKVTLIGNMK VSVELANVYR QQYRLAKETL AAQPKSKQFD FDEQAIFLKF 420 DLSSKALHKL IDMFTTIHQF SSLEQHTHIE GLDTMLKSLN NIIDDVKRKP YDLLDYSRNA 480 FDTDFLEFNV QINDLELQLQ GFVNASFEHI TSTEHALSLL AQFQAIMQRE TLQQDLENKY 540 MVIFQNYAKD LDAVQKLYEK NKYEPPVPRN APPVAGNIMW ARQLLRRIEA PMQLAQNKNL 600 LAAKESKKNI KTYNKVAKAL IEFETLWHQA WIKSIEQCKA GLAAPLLVQH PDTGKILVNF 660 DKEIMQLVRE AKYMQRFNIR CSSPSQMVLL QEEKFKFYHN QLTHLVREYE HVLGRGATIK 720 PLLRPHLDDM ERKIAPGFAV LTWTSLNIDG YLHRFKQGLA RLEELVRKVV DLTENRVDSN 780 LGAISSTLLV ELPTDRSFTY EGFVEQNRFQ KKQAELLAIR NEEVRRAIED LYTLVRNYPR 840 ENTEDVLDEK EVSLLVRHYS KNMYNAIMQC TLNSLQAMKR RLGSKTTTGI FFMERPFFDV 900 DVELKVPSVC MNPTLEEIQA AINQCAKKVL TISKQLPAWG MDNVATYHEM MRGDRRWVKA 960 VLRLTGSVEG IKTQVGEYIR TFDKYDFLWK EDLQAAYDHF MRSNPTLEAF EAELKKYMAI 1020 ETEVTMINGV NNIGALSLET HPLKNSLKAE AVSWKTQFAQ NLHKQCSDDL KLDNYIRDTN 1080 SKFHRKIEDL EDVRNVMAVL KEVREKESEI DNLIGPIEEM YGLLMRYEVR VPKEETTMVS 1140 DLRYGWKKLK KVATEVSDNL TRLQVGFKRE LIKEVKTFVV DAQMFRKDWE ANAMVPGLDP 1200 QEAVDRLRKF QQMFEVRKRK WENYSSGEEL FGLPVTQYPE LEQTEKEIQM LDRLYSLYVA 1260 VITTIKGYGD YFWVDVVEKI DEMGEQVQQY QNQSKKLPKL RDWPAYNACR KTIDDFLEML 1320 PLFQALTHKS MRERHWKEVM RVTGHELNLA EDHFKLQHLL DCNVLRYRED IEDLTGAAVK 1380 EEIIEVKLNQ LKADWATANL ALAEYKNRGP VILKPSDTSE LMEKLEESQM TLGSMATNRY 1440 SAPFRDEVQA WSIKLSTVSE IIEQWLMVQS MWQYMEAVFS GGDIVKQLPQ EAKRFLNIDK 1500 NFMKIVSNAL ETQNVINTCF GNELMKNMLP HLHEQLEMCQ KSLSAYLEQK RAEFPRFTCV 1560 GPHLLEICRW AHDPPSVVPH FQSGLFDSLS NVTFDRIDKT RMTEMFSQQN EKVEFERPVD 1620 AKGNIEVWLQ RLVDGMEDTV KQIIKRAVRN VAEMPLEDFV FGHPAQVSLL GIQFQWTAET 1680 QMALSSAKVD KTIMNKNMKK VDALLRDMVN ITVRLDLTKN QRTNLETCIT VHMHQKESTE 1740 DLVKKKIKDP TDFEWLKQVR FYWRDDKDTV IISICDVDFE YSFEYLGVKE RLVITPLTDI 1800 CYITLSQALG MFLGGAPAGP AGTGKTETTK DLGNTLGKYV VVFNCSDQFD YTYMGKIYKG 1860 LAQSGLWGCF DEFNRINLDV LSVCAQQVYC ICRTRERKKS FQFTDGTTVS LDPRVGFFIT 1920 MNPGYAGAQE LPENLKALFR GVTMMVPNRQ IIMKVKLAAA GYQENDILSK KFFVLYGLCE 1980 QQLSKQAHYD FGLRNILSVL RTAGASKRQS PDKSEVFLMM RTVRDMNMSK FVAEDVPLFL 2040 SLIDDLFPGL KADATRPDVN KDAEKVVLER GLQVHPTWMN KCIQLYETYL VRHGIMLVGP 2100 SGSGKSAICE CLAAALTELG TKHVIWRMNP KAITAPQMFG RRDDTTGDWT DGIFAVLWRR 2160 AAKNKNQNTW IVLDGPVDAI WIENLNTVLD DNKVLTLANG DRILMSAAMK AMFEPENLNN 2220 ASPATVSRAG IIYVSDVELG WEPPVKSWLQ KRDPTEACWA RLFSKYIDRM LEFVRISLKP 2280 VMYNEQVSIV GTVMTLLNGY LKSMKEAGTA MNDAKYERVF LYCMTWSLGG LLEMKERPLF 2340 DQELRTFAHN MPPKEEDSDT IFEFLVNTTD AEWLHWRHCV PVWTYPKNEE KPQYAQLVIP 2400 TLDSVRYGAL LNLSYNVDKA TLLVGGPGTA KTNTINQFIS KFNAETTANK TITFSSLTTP 2460 GIFQMSIEGA VEKRQGRTFG PPGGKQMCIF VDDISMPYIN EWGHQVTNEI VRQLLEQGGM 2520 YSLEKPIGDM KFITDVRYVA AMNTPGGGKN DIPNRLKRQF AIFNVPLPSV AAINGIFGKL 2580 VEGRFSRDVF CEEVVYVASK LVPLTITLWN RIQTKMLPTP AKFHYLFNMR ELSKVFQGVI 2640 LATRDRFNLA AGDSAVFGGN VASPEGYLLG LWIHECRRVF SDKLISYEDK NWVDKAVFDL 2700 CRDNFSSDLV KQVEEPIYFV DFLREPAVMM RPVEIVTPHP SFYYSVPGGL PEVRARVEGL 2760 QRKFNEESKV MKLELVLFTD CVTHLMRITR LLAWPGLGLL VGVGGSGKQS LSRLSAYIAG 2820 PTFYITKTYN VSNLFEHIKG LYKIAGFKGQ PVYFIFTDAE VKDEGFLEYI NQILMTGEVA 2880 GLLTKEDQDM IVNDIRPVMK HQAPGILDTY DNLYNFFLNR VRDNLHVVLC FSPVGAKFAR 2940 RAQQFPGLIN GCTIDWFCPG PKKRLTSVSG KFIDKFTMAC PKEVKNQLEL LMGHAHVFVT 3000 AACKEYFEKY RRYVYVTPKS YLSFLQGYKE LYAKKWSFTK ELAYQIEVAC QKMFEPKADV 3060 NKMKAELAVK NQTAVSAKEA EALLKQISES TAIAEKEKQK VAVIVDAVTK KASEIATVKD 3120 DAERDLAAAK PALDAALEAL NSIKDGDIKN LKALKKPPQI ITRIFDCVLV LRMLPVTKAE 3180 YTDEKGRMVQ VGNYPEAQKM MNQMSFLQDL KDFAKEQIND ETVELLEPYF MSEDFTFENA 3240 QKGSGNVAGL CNWAESMAKY HNVAKVVEPK IAKLREAEAE LKLATKEKNA AEERMAKVQA 3300 KLDEMQAQFD AAMAHKQALE DDAAATQRKM DSANALIGAL AGEEARWTAQ SKEFDVQIQR 3360 LTGDCALASA FVSYLGPFNK EFRELLLNRD FYGDCMKLNV PVTPHLQITK FLVDDSEVGE 3420 WNLQGLPTDE LSIQNGIMVT RASRYPVLVD PQGQGREWIK NREEANQLKT TQLNDKLFRN 3480 HLEECLAFGR PLLIENIEEE LDPLLDPVLE RRLVKKGKTW VVPLADKEVD FTETFRLFCT 3540 TRLPNPHFTP ELSAKVTVVD FTVTMAGLED QLLGKLISKE KKELEDQRQQ LLEEVQSYKK 3600 RIKQLEDDLL CRLSNSQGNL LDEHQELIDV LAVTKQTAQD VSEKLANASE TNKRINEACE 3660 EYRPVAHRAT LLYFLIAEFS VVNCMYQTSL AQFNQLYELA IDRSEKANMP SKRIHNIIEY 3720 MTYEIYLYVQ RGLFERHKII FALMLTNKVL TSAGKVKATD LDVFLKGGAA LDINSVRKKP 3780 KDWIPDLVWL NIIALSAMDA FRDIPDSVFR NDGLWRQWYD QEAPEMAKVP DYEDRLNKFE 3840 RMCVVKTFRE DRTLIAAADY IAEALGQRFV ESVPLNMEKR PGRRAMAKCP LICLLSPGPD 3900 PTKLIEDLAK KKKIKTLGVS MGQGQEVIAR KHMAAASLEG HWVLLQNTHL GLGYLTEVET 3960 FLVKEENVHE DFRLWITAEP HPQFPIGLLQ MGIKITNEAP VGIKAGLRAS YQWVNQDMLD 4020 MVSRQEWRQL LFVMCFLHSV VQEPQFGPIG WNVPYEFNQS DLSACVQFLQ NHLSEMDAKK 4080 APQPTWETVR YMISAIQYGS RITDDFDKLL MDTFAEKYFL QPVLQPSYEL FKDTRSSDGF 4140 SYRVPDSTDI ETFGSYIETL PGTESPEIFG LHPNADITFR TLQVQESIVT ILDTMPKGAG 4200 SGSGLSREDV VDKICEDLLS KAPPLFDKEE TKEKLKKLPG GPTLPLTVHL RQEIDRLNIV 4260 TRLTTTTLKN LALAIAGTIA AERGLIDALD ALFNARIPQQ WLSKSWEAST LGNWFTGLLQ 4320 RYDQLNKWLN LGRPKAYWMT GFFNPQGFLT AMKQEVNRKH RDKWALDDVV MSSEVTHRPK 4380 DFESLKEGAP EGVYVYGLYL DLRLDGRENR LMDSDPKKLF NPLPVLHVDG VLAKDKKRSG 4440 LYEAPKPYRV KARKGLNFIT TFSVRTEDDK SKWILPGVGI LCSID 4485 Gene Ontology GO:0005929; C: cilium; IEA: UniProtKB-KW GO:0005737; C: cytoplasm; IEA: UniProtKB-KW GO:0030286; C: dynein complex; IEA: UniProtKB-KW GO:0005874; C: microtubule; IEA: UniProtKB-KW GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0016887; F: ATPase activity; IEA: InterPro GO:0003777; F: microtubule motor activity; IEA: InterPro GO:0030030; P: cell projection organization; IEA: UniProtKB-KW GO:0007018; P: microtubule-based movement; IEA: InterPro Interpro InterPro; IPR003593; AAA+_ATPase InterPro; IPR011704; ATPase_dyneun-rel_AAA InterPro; IPR026983; DHC_fam InterPro; IPR024743; Dynein_HC_stalk InterPro; IPR024317; Dynein_heavy_chain_D4_dom InterPro; IPR004273; Dynein_heavy_dom InterPro; IPR013594; Dynein_heavy_dom-1 InterPro; IPR013602; Dynein_heavy_dom-2 InterPro; IPR027417; P-loop_NTPase Pfam SMART SMART; SM00382; AAA PROSITE PRINTS |