※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.57 
Molecular Weight
118504.41 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
FACT complex subunit SPT16; Facilitates chromatin transcription complex subunit SPT16; Global transcription factor group C protein 102 
Gene Name
SPT16; GTC102 
Created Date
2006-07-11 
Organism
Zea mays(Maize) 
NCBI Taxa ID
4577 
Phosphorylation Sites
Position
Peptide
Source
References
1018
DREHGAESDSEEERR
dbPPT
[1]
1020
EHGAESDSEEERRRR
dbPPT
[1]
513
LAGVGTGSGDGRGPA
dbPPT
[1]
Functional Description
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. SSRP1 binds specifically to double-stranded DNA (By similarity). 
Sequence Annotation
chain 1 1055 FACT complex subunit SPT16
coiled-coil region 313 333
coiled-coil region 480 503
coiled-coil region 768 789
compositionally biased region 924 991 Asp-rich (acidic)
Keyword
Chromosome,Coiled coil,Complete proteome,DNA damage,DNA repair,DNA replication,Nucleus,Reference proteome,Transcription,Transcription regulation 
Sequence Source
UniProt 
Protein Sequence
MADNGDAKGG SGAYAINIEN FSKRLKVFYD HWKEHKSDLW GSSDAIAIAT PPPSDDLRYL 60
KSSALDIWLL GYEFPETIIV FMHKQIHVLS SQKKGNLIGT LKKAANEAVG VDIVLHVKTK 120
NSDGADLMDD IVHAARNQSK SDKPVVGHIA KEAPEGKLLE TWIKKLSGSG LRLVDVTNGF 180
SELFAVKDTT EITCVKKAAY LTSSVLKNFV IPKLEKVIDE EKEVSHSSLM DDAEKAILDP 240
LKVKVKLKPD NVDICYPPVF QSGGKFDLKP GASSNDEYLY YDSASIIICA IGSKYSSYCS 300
NVARTYLIDA TPTQNKAYET LRKAHEAAIQ QVKPGNQMSA VYQAAVAVIE RDAPELLPNL 360
TKSAGTGIGL EFRESGLNLN AKNDRRIKKG MVFNVSLGLH NIQAETTSEK TKQFSLLLAD 420
TVLVNERGHE ILTAPCSKAF KDVAYSFNED DDAVAAEVKI KSKTIDVMPT KATLRSDNQE 480
MSKEELRRQH QAELARQKNE ETARRLAGVG TGSGDGRGPA RASNELVAYK NVNDVPFVRD 540
LVIQVDQKNE AVLLPIYGSM VPFHVSTVKS VTSHQDNRTC TIRIFFNVPG MPFSNDSKFN 600
SQGAIYLKEI TFRSKDPRHS SEVVQQIKTL RRQVASRESE RAERATLVTQ EKLQIGSNRM 660
KMMRLSDVWI RPAFGGRGRK LTGNLEAHFN GFRYSTSRSD ERVDIMFGNI KHAFFQPAEK 720
EMITLLHFHL HNHIMVGNKK TKDVQFYVEV MDVVQTLGGS RRSALDPDEI EEEQRERDRK 780
NRINMDFQNF VNKVNDHWSQ PQFKGLDLEF DVPLRELGFH GVPYKASAFI IPTSTCLVEL 840
IETPFLVVSL SEIEIVNLER VGFGTKNFDM AIVFKDFKKD VLRIDSIPSA SLDAIKEWLD 900
TTDLKYYESR LNLNWRPILK TIIDDPQKFI DDGGWEFLNM EASDSETEDT EESDQGYVPS 960
DAEPESESED DDSDSESLVE SDDDDEESDE DSEEEKGKTW EELEREASNA DREHGAESDS 1020
EEERRRRKAK TFGKSRAPER SSFKGAPPSK KPKFR 1055 
Gene Ontology
GO:0035101; C: FACT complex; IEA: EnsemblPlants/Gramene
GO:0005719; C: nuclear euchromatin; IEA: EnsemblPlants/Gramene
GO:0005730; C: nucleolus; IEA: EnsemblPlants/Gramene
GO:0006281; P: DNA repair; IEA: UniProtKB-KW
GO:0006260; P: DNA replication; IEA: UniProtKB-KW
GO:0006355; P: regulation of transcription, DNA-templated; IEA: UniProtKB-KW
GO:0006351; P: transcription, DNA-templated; IEA: UniProtKB-KW
GO:0010228; P: vegetative to reproductive phase transition of meristem; IEA: EnsemblPlants/Gramene 
Interpro
InterPro; IPR029149; Creatin/AminoP/Spt16_NTD
InterPro; IPR013719; DUF1747
InterPro; IPR029148; FACT-Spt16_Nlobe
InterPro; IPR013953; FACT_Spt16p
InterPro; IPR000994; Pept_M24_structural-domain
Pfam
Pfam; PF14826; FACT-Spt16_Nlob
Pfam; PF00557; Peptidase_M24
Pfam; PF08512; Rtt106
Pfam; PF08644; SPT16 
SMART
 
PROSITE
 
PRINTS