※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
6.39 
Molecular Weight
69917.57 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Flap endonuclease GEN-like 2; OsSEND-1; Single-strand DNA endonuclease 1 
Gene Name
SEND1; GEN2; Os08g0101600; LOC_Os08g01130; B1147B12.17 
Created Date
2008-01-15 
Organism
Oryza sativa subsp. japonica(Rice) 
NCBI Taxa ID
39947 
Phosphorylation Sites
Position
Peptide
Source
References
81
VTDGAIPSLKLATYR
dbPPT, P3DB
[1, 2]
Functional Description
Single-stranded DNA endonuclease activity in vitro. May not be active as double-stranded DNA endonuclease. 
Sequence Annotation
chain 1 641 Flap endonuclease GEN-like 2
region of interest 1 90 N-domain
region of interest 132 221 I-domain
metal ion-binding site 30 Magnesium 1
metal ion-binding site 76 Magnesium 1
metal ion-binding site 144 Magnesium 1
metal ion-binding site 146 Magnesium 1
metal ion-binding site 165 Magnesium 2
metal ion-binding site 167 Magnesium 2
metal ion-binding site 217 Magnesium 2
Keyword
Complete proteome,DNA damage,DNA repair,Endonuclease,Hydrolase,Magnesium,Metal-binding,Nuclease,Nucleus,Reference proteome 
Sequence Source
UniProt 
Protein Sequence
MGVKNLWDIL ESCKKKLPLH HLQNKKVCVD LSCWLVQMYS ANRSPAFAKD KVYLKNLFHR 60
IRALLALNCT LLFVTDGAIP SLKLATYRRR LGSISHAAKE SDQPNSHPSI SLRRNKGSEF 120
SCMIKEAKRL GMALGIPCLD GLEEAEAQCA SLDLESLCDG CFTSDSDAFL FGARTVYRDV 180
FIGEGGYVIC YEMEDIEKTL GFGRNSLISL AVLLGSDYSN GVNGFGPETA CRLVKSVGDN 240
LILDQILSNG VKATRKCKGK NSGNKVDDMC PKASSCEVGM TQDSDGQFRD VINAYLEPKC 300
HSPDSEAVQR VCGQHPFLRP QLQKICEEYF DWSPEKTDQY ILPKIAEREL RRFSDLRSAS 360
SALGIKPLLS EIPVPCPVLA IVKQRKVHGN ECYEVSWRNI EGLQVSVVPG DLVKSACPEK 420
ITEFLEKKGE EKKQKRRARP KKSGQAAVKD VDEQLQELLL GIEADSGGIL GATASVCQTL 480
TAAYTVAVED VVDLSSPSPP LRKLSKSQKK MMAEDVNVAG MNMNKMESES SFSTQSSTSD 540
VDNQLIDLSS PLAGGDNGMK GGRRALADIS NVGSHSTETD GGGGGGGGVA SVGHGTTIDL 600
SSPSPAIGDR SRVHHDDDDV IHERKARDLR MFLDSIRNEL Y 641 
Gene Ontology
GO:0005634; C: nucleus; IEA: UniProtKB-SubCell
GO:0003677; F: DNA binding; IEA: InterPro
GO:0004519; F: endonuclease activity; IEA: UniProtKB-KW
GO:0046872; F: metal ion binding; IEA: UniProtKB-KW
GO:0006281; P: DNA repair; IEA: UniProtKB-KW 
Interpro
InterPro; IPR020045; 5-3_exonuclease_C
InterPro; IPR008918; HhH2
InterPro; IPR029060; PIN_domain-like
InterPro; IPR006086; XPG-I_dom
InterPro; IPR006085; XPG_DNA_repair_N
Pfam
Pfam; PF00867; XPG_I
Pfam; PF00752; XPG_N 
SMART
SMART; SM00279; HhH2
SMART; SM00484; XPGI
SMART; SM00485; XPGN 
PROSITE
 
PRINTS