※ dbPPT Protein Information
Tag | Content | ||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 5.31 | ||||||||||||||||||||||||||||||
Molecular Weight | 101045.99 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | DNA (cytosine-5)-methyltransferase 1; Chromomethylase 1; DNA cytosine methyltransferase MET2a; Zea methyltransferase2; Zmet2 | ||||||||||||||||||||||||||||||
Gene Name | MET2A | ||||||||||||||||||||||||||||||
Created Date | 2006-07-25 | ||||||||||||||||||||||||||||||
Organism | Zea mays(Maize) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 4577 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Involved in the CpXpG methylation and in gene silencing. Sequence Annotation chain 1 912 DNA (cytosine-5)-methyltransferase 1 domain 184 309 BAH domain 341 872 SAM-dependent MTase C5-type domain 441 504 Chromo compositionally biased region 31 35 Poly-Glu compositionally biased region 73 107 Glu-rich active site 517 helix 144 150 helix 152 154 strand 172 175 strand 177 181 strand 184 187 strand 191 194 strand 203 213 strand 218 227 helix 228 230 helix 234 238 strand 250 261 helix 262 264 strand 265 268 strand 271 273 helix 280 289 strand 291 299 helix 301 303 strand 304 307 strand 339 346 helix 352 364 strand 366 376 helix 378 387 strand 391 396 helix 398 414 strand 443 452 strand 454 456 strand 458 466 helix 471 473 strand 475 479 helix 480 482 helix 486 499 strand 509 513 strand 519 521 helix 522 526 turn 532 534 helix 539 551 strand 554 561 helix 562 565 helix 567 570 helix 571 582 strand 586 593 helix 594 597 strand 604 611 helix 635 637 helix 658 662 strand 675 677 helix 686 691 turn 695 699 strand 703 706 helix 724 732 helix 741 743 strand 747 749 helix 751 753 strand 755 757 strand 759 761 strand 769 773 helix 775 779 helix 780 783 strand 798 800 strand 807 813 strand 815 820 helix 823 829 helix 842 851 helix 855 870 strand 878 880 strand 884 887 Keyword 3D-structure,Chromatin regulator,Complete proteome,DNA-binding,Methyltransferase,Nucleus,Reference proteome,S-adenosyl-L-methionine,Transcription,Transcription regulation,Transferase Sequence Source UniProt Protein Sequence MAPSSPSPAA PTRVSGRKRA AKAEEIHQNK EEEEEVAAAS SAKRSRKAAS SGKKPKSPPK 60 QAKPGRKKKG DAEMKEPVED DVCAEEPDEE ELAMGEEEAE EQAMQEEVVA VAAGSPGKKR 120 VGRRNAAAAA GDHEPEFIGS PVAADEARSN WPKRYGRSTA AKKPDEEEEL KARCHYRSAK 180 VDNVVYCLGD DVYVKAGENE ADYIGRITEF FEGTDQCHYF TCRWFFRAED TVINSLVSIS 240 VDGHKHDPRR VFLSEEKNDN VLDCIISKVK IVHVDPNMDP KAKAQLIESC DLYYDMSYSV 300 AYSTFANISS ENGQSGSDTA SGISSDDVDL ETSSSMPTRT ATLLDLYSGC GGMSTGLCLG 360 AALSGLKLET RWAVDFNSFA CQSLKYNHPQ TEVRNEKADE FLALLKEWAV LCKKYVQDVD 420 SNLASSEDQA DEDSPLDKDE FVVEKLVGIC YGGSDRENGI YFKVQWEGYG PEEDTWEPID 480 NLSDCPQKIR EFVQEGHKRK ILPLPGDVDV ICGGPPCQGI SGFNRYRNRD EPLKDEKNKQ 540 MVTFMDIVAY LKPKYVLMEN VVDILKFADG YLGKYALSCL VAMKYQARLG MMVAGCYGLP 600 QFRMRVFLWG ALSSMVLPKY PLPTYDVVVR GGAPNAFSQC MVAYDETQKP SLKKALLLGD 660 AISDLPKVQN HQPNDVMEYG GSPKTEFQRY IRLSRKDMLD WSFGEGAGPD EGKLLDHQPL 720 RLNNDDYERV QQIPVKKGAN FRDLKGVRVG ANNIVEWDPE IERVKLSSGK PLVPDYAMSF 780 IKGKSLKPFG RLWWDETVPT VVTRAEPHNQ VIIHPTQARV LTIRENARLQ GFPDYYRLFG 840 PIKEKYIQVG NAVAVPVARA LGYCLGQAYL GESEGSDPLY QLPPSFTSVG GRTAGQARAS 900 PVGTPAGEVV EQ 912 Gene Ontology GO:0005634; C: nucleus; IEA: UniProtKB-SubCell GO:0003682; F: chromatin binding; IEA: InterPro GO:0003886; F: DNA (cytosine-5-)-methyltransferase activity; IEA: UniProtKB-EC GO:0003677; F: DNA binding; IEA: UniProtKB-KW GO:0016568; P: chromatin modification; IEA: UniProtKB-KW GO:0006355; P: regulation of transcription, DNA-templated; IEA: UniProtKB-KW GO:0006351; P: transcription, DNA-templated; IEA: UniProtKB-KW Interpro Pfam SMART PROSITE PRINTS PR00105; C5METTRFRASE |