※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.18 
Molecular Weight
58566.51 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Importin subunit alpha-1b 
Gene Name
Os05g0155500; LOC_Os05g06350 
Created Date
2005-04-26 
Organism
Oryza sativa subsp. japonica(Rice) 
NCBI Taxa ID
39947 
Phosphorylation Sites
Position
Peptide
Source
References
195
LGNVAGDSPKCRDLV
dbPPT, P3DB
[1, 2]
107
TQFRKLLSIERSPPI
dbPPT, P3DB
[1, 2]
Functional Description
Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. In conjunction with importin beta-1, mediates the nuclear envelope docking, and the subsequent translocation into the nucleus of the constitutive morphogenetic 1 (COP1) protein containing bipartite NLS motif. 
Sequence Annotation
chain 1 534 Importin subunit alpha-1b
domain 1 58 IBB
repeat 111 151 ARM 1
repeat 154 193 ARM 2
repeat 196 236 ARM 3
repeat 238 277 ARM 4
repeat 280 319 ARM 5
repeat 322 362 ARM 6
repeat 365 404 ARM 7
repeat 408 447 ARM 8
Keyword
Complete proteome,Cytoplasm,Protein transport,Reference proteome,Repeat,Transport 
Sequence Source
UniProt 
Protein Sequence
MSLRPSERAE VRRSRYKVAV DADEGRRRRE DNMVEIRKSR REESLLKKRR DGLPAAAAAA 60
AAASPLLAHS SALQQKLEGL PAMVQAVQSD DSAVQLEATT QFRKLLSIER SPPIEEVINT 120
GVVPRFIAFL QREDYPQLQF EAAWALTNIA SGTSDNTKVV VESGAVPIFV KLLSSPSEDV 180
REQAVWALGN VAGDSPKCRD LVLASGGLYP LLQQLNEHAK LSMLRNATWT LSNFCRGKPQ 240
PNFEQVKPAL SALQRLIHSQ DEEVLTDACW ALSYLSDGTN DKIQAVIESG VFPRLVELLM 300
HPSASVLIPA LRTVGNIVTG DDMQTQCVID HQALPCLLNL LTNNHKKSIK KEACWTISNI 360
TAGNREQIQA VINANIIAPL VHLLQTAEFD IKKEAAWAIS NATSGGTHDQ IKYLVAQGCI 420
KPLCDLLVCP DPRIVTVCLE GLENILKVGE AEKNLGAGDV NSYAQMIDDA EGLEKIENLQ 480
SHDNTEIYEK AVKMLESYWL EEEDDAMPSG DNAQNGFNFG NQQPNVPSGG FNFG 534 
Gene Ontology
GO:0005634; C: nucleus; IEA: InterPro
GO:0048471; C: perinuclear region of cytoplasm; IEA: UniProtKB-SubCell
GO:0008565; F: protein transporter activity; IEA: InterPro
GO:0006606; P: protein import into nucleus; IEA: InterPro 
Interpro
InterPro; IPR011989; ARM-like
InterPro; IPR016024; ARM-type_fold
InterPro; IPR000225; Armadillo
InterPro; IPR002652; Importin-a_IBB
InterPro; IPR024931; Importing_su_alpha
Pfam
Pfam; PF00514; Arm
Pfam; PF01749; IBB 
SMART
SMART; SM00185; ARM 
PROSITE
PS50176; ARM_REPEAT
PS51214; IBB 
PRINTS