※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||
Theoretical PI | 4.47 | ||||||||||||||||||||||||||||||||||
Molecular Weight | 48309.02 | ||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||
Protein Name | Calreticulin | ||||||||||||||||||||||||||||||||||
Gene Name | Os07g0246200; LOC_Os07g14270; OJ1058_C08.34-1; OJ1058_C08.34-2; OSJNBa0003K21.18-1; OSJNBa0003K21.18-2 | ||||||||||||||||||||||||||||||||||
Created Date | 2000-12-01 | ||||||||||||||||||||||||||||||||||
Organism | Oryza sativa subsp. japonica(Rice) | ||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 39947 | ||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Sequence Annotation signal peptide 1 29 chain 30 424 Calreticulin repeat 201 212 1-1 repeat 220 231 1-2 repeat 237 248 1-3 repeat 255 266 1-4 repeat 270 280 2-1 repeat 284 294 2-2 repeat 298 308 2-3 region of interest 201 266 4 X approximate repeats region of interest 270 308 3 X approximate repeats short sequence motif 421 424 Prevents secretion from ER compositionally biased region 362 420 Asp/Glu/Lys-rich binding site 119 Carbohydrate binding site 121 Carbohydrate binding site 138 Carbohydrate binding site 145 Carbohydrate binding site 328 Carbohydrate glycosylation site 61 N-linked (GlcNAc...) disulfide bond 115 147 splice variant 422 424 In isoform 2. Keyword Alternative splicing,Calcium,Chaperone,Complete proteome,Direct protein sequencing,Disulfide bond,Endoplasmic reticulum,Glycoprotein,Lectin,Metal-binding,Reference proteome,Repeat,Signal,Zinc Sequence Source UniProt Protein Sequence MAIRARSSSY AAAAVALALA LASVAAVAGE VFFQEKFEDG WESRWVKSEW KKDENMAGEW 60 NHTSGKWNGD PEDKGIQTSE DYRFYAISAE YPEFSNKDKT LVLQFSVKHE QKLDCGGGYV 120 KLLGGDVDQK KFGGDTPYSI MFGPDICGYS TKKVHTIFTK NDKNHLIKKD VPCETDQLSH 180 VYTLIIHPDA TYTILIDNVE KQSGSIYEHW DILPPKQIKD PEAKKPEDWD DKEYIPDPED 240 KKPEGYDDIP KEIPDPDAKK PEDWDDEEDG EWTAPTIPNP EYKGPWKQKK IKNPNYQGKW 300 KAPMIDNPDF KDDPYIYAFD SLKYIGIELW QVKSGTLFDN FLITDDPELA KTFAEETWGK 360 HKDAEKAAFD EAEKKKEEEE AAKAGEDDDD LDDEDAEDED KADEKADSDA EDGKDSDDEK 420 HDEL 424 Gene Ontology GO:0005788; C: endoplasmic reticulum lumen; ISS: Gramene GO:0005509; F: calcium ion binding; ISS: Gramene GO:0051082; F: unfolded protein binding; ISS: Gramene GO:0007275; P: multicellular organismal development; ISS: Gramene GO:0006457; P: protein folding; IEA: InterPro Interpro Pfam Pfam; PF00262; Calreticulin SMART PROSITE PRINTS PR00626; CALRETICULIN |