※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Theoretical PI | 5.88 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight | 116858.4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Calcium-transporting ATPase 10, plasma membrane-type; Ca(2+)-ATPase isoform 10 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | ACA10; At4g29900; F27B13.140 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Created Date | 2001-01-11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the endoplasmic reticulum (By similarity). Sequence Annotation initiator methionine 1 Removed chain 2 1069 Calcium-transporting ATPase 10, plasma membrane-type topological domain 2 180 Cytoplasmic transmembrane region 181 201 Helical; topological domain 202 219 Lumenal transmembrane region 220 240 Helical; topological domain 241 369 Cytoplasmic transmembrane region 370 389 Helical; topological domain 390 426 Lumenal transmembrane region 427 444 Helical; topological domain 445 844 Cytoplasmic transmembrane region 845 863 Helical; topological domain 864 874 Lumenal transmembrane region 875 895 Helical; topological domain 896 915 Cytoplasmic transmembrane region 916 938 Helical; topological domain 939 951 Lumenal transmembrane region 952 973 Helical; topological domain 974 991 Cytoplasmic transmembrane region 992 1013 Helical; topological domain 1014 1023 Lumenal transmembrane region 1024 1045 Helical; topological domain 1046 1069 Cytoplasmic region of interest 42 53 Interaction with calmodulin active site 482 4-aspartylphosphate intermediate metal ion-binding site 789 Magnesium metal ion-binding site 793 Magnesium modified residue 2 N-acetylserine Keyword Acetylation,ATP-binding,Calcium,Calcium transport,Calmodulin-binding,Complete proteome,Hydrolase,Ion transport,Magnesium,Membrane,Metal-binding,Nucleotide-binding,Reference proteome,Transmembrane,Transmembrane helix,Transport Sequence Source UniProt Protein Sequence MSGQFNNSPR GEDKDVEAGT SSFTEYEDSP FDIASTKNAP VERLRRWRQA ALVLNASRRF 60 RYTLDLKREE DKKQMLRKMR AHAQAIRAAH LFKAAASRVT GIASPLPTPG GGDFGIGQEQ 120 IVSISRDQNI GALQELGGVR GLSDLLKTNL EKGIHGDDDD ILKRKSAFGS NTYPQKKGRS 180 FWRFVWEASQ DLTLIILIVA AVASLALGIK TEGIEKGWYD GISIAFAVLL VIVVTATSDY 240 RQSLQFQNLN EEKRNIRLEV TRDGRRVEIS IYDIVVGDVI PLNIGDQVPA DGVLVAGHSL 300 AVDESSMTGE SKIVQKNSTK HPFLMSGCKV ADGNGTMLVT GVGVNTEWGL LMASVSEDNG 360 GETPLQVRLN GVATFIGIVG LTVAGVVLFV LVVRYFTGHT KNEQGGPQFI GGKTKFEHVL 420 DDLVEIFTVA VTIVVVAVPE GLPLAVTLTL AYSMRKMMAD KALVRRLSAC ETMGSATTIC 480 SDKTGTLTLN EMTVVECYAG LQKMDSPDSS SKLPSAFTSI LVEGIAHNTT GSVFRSESGE 540 IQVSGSPTER AILNWAIKLG MDFDALKSES SAVQFFPFNS EKKRGGVAVK SPDSSVHIHW 600 KGAAEIVLGS CTHYMDESES FVDMSEDKMG GLKDAIDDMA ARSLRCVAIA FRTFEADKIP 660 TDEEQLSRWE LPEDDLILLA IVGIKDPCRP GVKNSVLLCQ QAGVKVRMVT GDNIQTAKAI 720 ALECGILASD SDASEPNLIE GKVFRSYSEE ERDRICEEIS VMGRSSPNDK LLLVQSLKRR 780 GHVVAVTGDG TNDAPALHEA DIGLAMGIQG TEVAKEKSDI IILDDNFESV VKVVRWGRSV 840 YANIQKFIQF QLTVNVAALV INVVAAISAG EVPLTAVQLL WVNLIMDTLG ALALATEPPT 900 DHLMDRAPVG RREPLITNIM WRNLFIQAMY QVTVLLILNF RGISILHLKS KPNAERVKNT 960 VIFNAFVICQ VFNEFNARKP DEINIFRGVL RNHLFVGIIS ITIVLQVVIV EFLGTFASTT 1020 KLDWEMWLVC IGIGSISWPL AVIGKLIPVP ETPVSQYFRI NRWRRNSSG 1069 Gene Ontology GO:0016021; C: integral component of membrane; IEA: UniProtKB-KW GO:0005886; C: plasma membrane; IDA: TAIR GO:0009506; C: plasmodesma; IDA: TAIR GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0005388; F: calcium-transporting ATPase activity; ISS: TAIR GO:0046872; F: metal ion binding; IEA: UniProtKB-KW Interpro InterPro; IPR006408; ATPase_P-typ_Ca-transp_plasma InterPro; IPR006068; ATPase_P-typ_cation-transptr_C InterPro; IPR004014; ATPase_P-typ_cation-transptr_N InterPro; IPR023299; ATPase_P-typ_cyto_domN InterPro; IPR018303; ATPase_P-typ_P_site InterPro; IPR023298; ATPase_P-typ_TM_dom InterPro; IPR008250; ATPase_P-typ_transduc_dom_A InterPro; IPR024750; Ca_ATPase_N_dom InterPro; IPR001757; Cation_transp_P_typ_ATPase InterPro; IPR023214; HAD-like_dom Pfam SMART SMART; SM00831; Cation_ATPase_N PROSITE PS00154; ATPASE_E1_E2 PRINTS PR00119; CATATPASE |