※ dbPPT Protein Information
| Tag | Content | ||||||||||||||||||||||||||||||
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 4.65 | ||||||||||||||||||||||||||||||
Molecular Weight | 28450.79 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1; AtMTN1; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; MTA/SAH nucleosidase 1; AtMTAN1; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase | ||||||||||||||||||||||||||||||
Gene Name | MTN1; MTAN; MTAN1; At4g38800; T9A14.80 | ||||||||||||||||||||||||||||||
Created Date | 2010-11-30 | ||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis. Inactive towards S-adenosylhomocysteine (SAH/AdoHcy). Sequence Annotation chain 1 267 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 region of interest 116 118 Substrate binding region of interest 199 202 Substrate binding active site 38 Proton acceptor active site 225 Proton donor binding site 181 Substrate; via carbonyl oxygen strand 28 32 helix 36 45 strand 63 69 strand 72 78 turn 83 85 strand 86 88 helix 92 106 strand 109 119 helix 121 123 strand 130 140 helix 148 153 helix 162 168 strand 171 177 helix 185 193 strand 197 202 helix 203 212 strand 217 226 strand 229 231 helix 233 259 helix 264 266 Keyword 3D-structure,Amino-acid biosynthesis,Complete proteome,Hydrolase,Methionine biosynthesis,Reference proteome Sequence Source UniProt Protein Sequence MAPHGDGLSD IEEPEVDAQS EILRPISSVV FVIAMQAEAL PLVNKFGLSE TTDSPLGKGL 60 PWVLYHGVHK DLRINVVCPG RDAALGIDSV GTVPASLITF ASIQALKPDI IINAGTCGGF 120 KVKGANIGDV FLVSDVVFHD RRIPIPMFDL YGVGLRQAFS TPNLLKELNL KIGRLSTGDS 180 LDMSTQDETL IIANDATLKD MEGAAVAYVA DLLKIPVVFL KAVTDLVDGD KPTAEEFLQN 240 LTVVTAALEG TATKVINFIN GRNLSDL 267 Gene Ontology GO:0005829; C: cytosol; IDA: TAIR GO:0005886; C: plasma membrane; IDA: TAIR GO:0008782; F: adenosylhomocysteine nucleosidase activity; IEA: UniProtKB-EC GO:0008930; F: methylthioadenosine nucleosidase activity; IDA: TAIR GO:0019509; P: L-methionine salvage from methylthioadenosine; IDA: TAIR GO:0009116; P: nucleoside metabolic process; IEA: InterPro GO:0000003; P: reproduction; IGI: TAIR GO:0001944; P: vasculature development; IGI: TAIR Interpro Pfam Pfam; PF01048; PNP_UDP_1 SMART PROSITE PRINTS |