※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||
Theoretical PI | 5.45 | ||||||||||||||||||||||||||||||||||
Molecular Weight | 105070.61 | ||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||
Protein Name | DNA mismatch repair protein MSH2; MUS1 | ||||||||||||||||||||||||||||||||||
Gene Name | MUS1 | ||||||||||||||||||||||||||||||||||
Created Date | 2000-12-01 | ||||||||||||||||||||||||||||||||||
Organism | Zea mays(Maize) | ||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 4577 | ||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Involved in postreplication mismatch repair. Binds specifically to DNA containing mismatched nucleotides thus providing a target for the excision repair processes characteristic of postreplication mismatch repair (By similarity). Sequence Annotation chain 1 942 DNA mismatch repair protein MSH2 nucleotide phosphate-binding region 667 674 ATP Keyword ATP-binding,Complete proteome,DNA damage,DNA repair,DNA-binding,Nucleotide-binding,Nucleus,Reference proteome Sequence Source UniProt Protein Sequence MEGDDFTPEG GKLPEFKLDA RQAQGFISFF KKLPQDPRAV RLFDRRDYYT AHGENATFIA 60 RTYYHTMSAL RQLGSSSDGI LSASVSKAMF ETIARNILLE RTDCTLELYE GSGSNWRLTK 120 SGTPGNIGSF EDILFANNDM EDSPVIVALF PACRESQLYV GLSFLDMTNR KLGLAEFPED 180 SRFTNVESAL VALGCKECLL PADCEKSIDL NPLQDVISNC NVLLTEKKKA DFKSRDLAQD 240 LGRIIRGSVE PVRDLLSQFD YALGPLGALL SYAELLADDT NYGNYTIEKY NLNCYMRLDS 300 AAVRALNIAE GKTDVNKNFS LFGLMNRTCT VGMGKRLLNR WLKQPLLDVN EINNRLDMVQ 360 AFVEDPELRQ GLRQQLKRIS DIDRLTHSLR KKSANLQPVV KLYQSCSRIP YIKGILQQYN 420 GQFSTLIRSK FLEPLEEWMA KNRFGRFSSL VETAIDLAQL ENGEYRISPL YSSDLGVLKD 480 ELSVVENHIN NLHVDTASDL DLSVDKQLKL EKGSLGHVFR MSKKEEQKVR KKLTGSYLII 540 ETRKDGVKFT NSKLKNLSDQ YQALFGEYTS CQKKVVGDVV RVSGTFSEVF ENFAAVLSEL 600 DVLQSFADLA TSCPVPYVRP DITASDEGDI VLLGSRHPCL EAQDGVNFIP NDCTLVRGKS 660 WFQIITGPNM GGKSTFIRQV GVNVLMAQVG SFVPCDQASI SVRDCIFARV GAGDCQLHGV 720 STFMQEMLET ASILKGASDK SLIIIDELGR GTSTYDGFGL AWAICEHLME VTRAPTLFAT 780 HFHELTALAH RNDDEHQHIS DIGVANYHVG AHIDPLSRKL TMLYKVEPGA CDQSFGIHVA 840 EFANFPEAVV ALAKSKAAEL EDFSTTPTFS DDLKDEVGSK RKRVFSPDDI TRGAARARLF 900 LEEFAALPMD EMDGSKILEM ATKMKADLQK DAADNPWLQQ FF 942 Gene Ontology GO:0032301; C: MutSalpha complex; IEA: InterPro GO:0032302; C: MutSbeta complex; IEA: InterPro GO:0005886; C: plasma membrane; IEA: EnsemblPlants/Gramene GO:0005524; F: ATP binding; IEA: UniProtKB-KW GO:0003684; F: damaged DNA binding; IEA: EnsemblPlants/Gramene GO:0030983; F: mismatched DNA binding; IEA: InterPro GO:0006298; P: mismatch repair; IEA: InterPro GO:0045128; P: negative regulation of reciprocal meiotic recombination; IEA: EnsemblPlants/Gramene GO:0006290; P: pyrimidine dimer repair; IEA: EnsemblPlants/Gramene Interpro InterPro; IPR011184; DNA_mismatch_repair_MSH2 InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N InterPro; IPR000432; DNA_mismatch_repair_MutS_C InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp InterPro; IPR007696; DNA_mismatch_repair_MutS_core InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom InterPro; IPR027417; P-loop_NTPase Pfam SMART PROSITE PS00486; DNA_MISMATCH_REPAIR_2 PRINTS |