※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Theoretical PI | 6.21 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight | 80290.87 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Double-strand break repair protein MRE11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | MRE11; At5g54260; MDK4.8 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Created Date | 2001-09-26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity). Sequence Annotation chain 1 720 Double-strand break repair protein MRE11 active site 125 Proton donor Keyword Complete proteome,DNA damage,DNA repair,Endonuclease,Exonuclease,Hydrolase,Manganese,Meiosis,Nuclease,Nucleus,Reference proteome Sequence Source UniProt Protein Sequence MSREDFSDTL RVLVATDCHL GYMEKDEIRR HDSFKAFEEI CSIAEEKQVD FLLLGGDLFH 60 ENKPSRTTLV KAIEILRRHC LNDKPVQFQV VSDQTVNFQN AFGQVNYEDP HFNVGLPVFS 120 IHGNHDDPAG VDNLSAIDIL SACNLVNYFG KMVLGGSGVG QITLYPILMK KGSTTVALYG 180 LGNIRDERLN RMFQTPHAVQ WMRPEVQEGC DVSDWFNILV LHQNRVKSNP KNAISEHFLP 240 RFLDFIVWGH EHECLIDPQE VSGMGFHITQ PGSSVATSLI DGESKPKHVL LLEIKGNQYR 300 PTKIPLTSVR PFEYTEIVLK DESDIDPNDQ NSILEHLDKV VRNLIEKASK KAVNRSEIKL 360 PLVRIKVDYS GFMTINPQRF GQKYVGKVAN PQDILIFSKA SKKGRSEANI DDSERLRPEE 420 LNQQNIEALV AESNLKMEIL PVNDLDVALH NFVNKDDKLA FYSCVQYNLQ ETRGKLAKDS 480 DAKKFEEDDL ILKVGECLEE RLKDRSTRPT GSSQFLSTGL TSENLTKGSS GIANASFSDD 540 EDTTQMSGLA PPTRGRRGSS TANTTRGRAK APTRGRGRGK ASSAMKQTTL DSSLGFRQSQ 600 RSASAAASAA FKSASTIGED DVDSPSSEEV EPEDFNKPDS SSEDDESTKG KGRKRPATTK 660 RGRGRGSGTS KRGRKNESSS SLNRLLSSKD DDEDEDDEDR EKKLNKSQPR VTRNYGALRR 720 Gene Ontology GO:0000785; C: chromatin; IDA: TAIR GO:0000791; C: euchromatin; IDA: TAIR GO:0000795; C: synaptonemal complex; IDA: TAIR GO:0004519; F: endonuclease activity; IEA: UniProtKB-KW GO:0004527; F: exonuclease activity; IEA: UniProtKB-KW GO:0030145; F: manganese ion binding; IEA: InterPro GO:0006302; P: double-strand break repair; IEA: InterPro GO:0007126; P: meiotic nuclear division; IEA: UniProtKB-KW Interpro Pfam SMART PROSITE PRINTS |