※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.52 
Molecular Weight
105069.34 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Eukaryotic translation initiation factor 3 subunit C; eIF3c; Eukaryotic translation initiation factor 3 subunit 8; eIF3 p110 
Gene Name
TIF3C1; AM3-1 
Created Date
2000-05-30 
Organism
Medicago truncatula(Barrel medic Medicago tribuloides) 
NCBI Taxa ID
3880 
Phosphorylation Sites
Position
Peptide
Source
References
210
LRKPEPVSDSETSEL
dbPPT, P3DB
[1, 2]
212
KPEPVSDSETSELGN
dbPPT, P3DB
[1, 2]
215
PVSDSETSELGNDRP
dbPPT, P3DB
[1, 2]
Functional Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). 
Sequence Annotation
chain 1 935 Eukaryotic translation initiation factor 3 subunit C
domain 663 793 PCI
Keyword
Cytoplasm,Initiation factor,Protein biosynthesis 
Sequence Source
UniProt 
Protein Sequence
MTSRFFYQGG DQSDTDDEPT DIDDEPSDTE PAPTDPNGKS KYLAGGNADD SDDDDGQKRV 60
VKSAKDKRFD EMASTVDQIK NAIKINDWVS LQESFDKINK QLEKVMRVIE SQKIPNLYIK 120
ALVMLEDFLA QASANKDAKK KMSPSNAKAF NSMKQKLKKN NKQYEDLIIK CRESPESEGE 180
KDEDDEDSDE YESDDEMIEP DQLRKPEPVS DSETSELGND RPGDDGDAPW DQKLSKKDRL 240
LEKMFMKKPS EITWDTVNKK FKEILEARGR KGTGRFEQVE QLTFLTKVAK TPAQKLQILF 300
SVVSAQFDVN PGLSGHMPIS VWKKCVQNML VILDILVQHP NIKVDDSVEL DENETKKGDD 360
YNGPINVWGN LVAFLEKIDA EFFKSLQCID PHTREYVERL RDEPQFVVLA QNVQEYLESI 420
GDFKASSKVA LKRVELIYYK PHEVYEATRK LAEMTVEGDN GEMSEEPKGF EDTRIPAPFV 480
VTLELVARKP TFPENSRTLM DVLVSLIYKY GDERTKARAM LCDIYHHALL DEFAVARDLL 540
LMSHLQENVH HMDISTQILF NRAMSQLGLC AFRAGLVSEA HGCLSELYSG GRVKELLAQG 600
VSQSRYHEKT PEQERLERRR QMPYHMHINL ELLESVHLTS AMLLEVPNMA ANVHDAKRKI 660
ISKNFRRLLE VSEKQTFTGP PETVRDHVMA ATRVLINGDF QKAFDIIASL DVWKFVKNRD 720
AVLEMLKDKI KEEALRTYLF TFSSSYDSLS VVQLTNFFDL SLPRVHSIVS RMMVNEELHA 780
SWDQPTGCII FRNVEHSRVQ ALAFQLTEKL SILAESNERA TEARLGGGGL DLPPRRRDGQ 840
DYAAAAAGGG SGTSSGGRWQ DLSYSQTRQG SGRTGYGGGR ALSFSQAGGS GGYSRGRGTG 900
GGGYQNSGRT QGGSALRGPH GDTSTRMVSL RGVRA 935 
Gene Ontology
GO:0016282; C: eukaryotic 43S preinitiation complex; IEA: UniProtKB-HAMAP
GO:0033290; C: eukaryotic 48S preinitiation complex; IEA: UniProtKB-HAMAP
GO:0005852; C: eukaryotic translation initiation factor 3 complex; IEA: UniProtKB-HAMAP
GO:0003743; F: translation initiation factor activity; IEA: UniProtKB-HAMAP
GO:0001731; P: formation of translation preinitiation complex; IEA: UniProtKB-HAMAP
GO:0006446; P: regulation of translational initiation; IEA: UniProtKB-HAMAP 
Interpro
InterPro; IPR027516; EIF3C
InterPro; IPR008905; EIF3C_N_dom
InterPro; IPR000717; PCI_dom
InterPro; IPR011991; WHTH_DNA-bd_dom
Pfam
Pfam; PF05470; eIF-3c_N
Pfam; PF01399; PCI 
SMART
SMART; SM00088; PINT 
PROSITE
 
PRINTS