※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
6.69 
Molecular Weight
85395.8 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2 
Gene Name
FIS2; At2g35670; T20F21.14 
Created Date
2003-05-16 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
491
KNVDNVPSPPKTRSS
dbPPT, P3DB
[1, 2]
277
TQLAIAESSEPKVPH
dbPPT, P3DB
[1, 2]
268
EKISDILTTTQLAIA
dbPPT, P3DB
[1, 2]
278
QLAIAESSEPKVPHV
dbPPT, P3DB
[1, 2]
Functional Description
Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization. Regulates the anteroposterior organization of the endosperm. 
Sequence Annotation
chain 1 755 Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2
repeat 245 266 A-1
repeat 267 283 B-1
repeat 284 306 A-2
repeat 307 329 A-3
repeat 330 351 A-4
repeat 352 373 A-5
repeat 374 390 B-2
repeat 405 421 B-3
repeat 422 443 A-6
repeat 444 460 B-4
repeat 461 483 A-7
repeat 484 504 A-8
repeat 505 521 B-5
repeat 522 544 A-9
repeat 545 565 A-10
repeat 566 582 B-6
zinc finger region 134 157 C2H2-type
region of interest 245 565 10 X approximate repeat A
region of interest 267 582 6 X approximate repeat B
region of interest 606 684 VEFS-box
compositionally biased region 16 64 Asp-rich
Keyword
Complete proteome,Developmental protein,Metal-binding,Nucleus,Polymorphism,Reference proteome,Repeat,Repressor,Transcription,Transcription regulation,Zinc,Zinc-finger 
Sequence Source
UniProt 
Protein Sequence
MARKSIRGKE VVMVSDDDDD DDDDVDDDKN IIKCVKPLTV YKNLETPTDS DDNDDDDDDD 60
VDVDENIIKY IKPVAVYKKL ETRSKNNPYF LRRSLKYIIQ AKKKKKSNSG GKIRFNYRDV 120
SNKMTLKAEV VENFSCPFCL IPCGGHEGLQ LHLKSSHDAF KFEFYRAEKD HGPEVDVSVK 180
SDTIKFGVLK DDVGNPQLSP LTFCSKNRNQ RRQRDDSNNV KKLNVLLMEL DLDDLPRGTE 240
NDSTHVNDDN VSSPPRAHSS EKISDILTTT QLAIAESSEP KVPHVNDGNV SSPPRAHSSA 300
EKNESTHVND DDDVSSPPRA HSLEKNESTH VNEDNISSPP KAHSSKKNES THMNDEDVSF 360
PPRTRSSKET SDILTTTQPA IVEPSEPKVR RVSRRKQLYA KRYKARETQP AIAESSEPKV 420
LHVNDENVSS PPEAHSLEKA SDILTTTQPA IAESSEPKVP HVNDENVSST PRAHSSKKNK 480
STRKNVDNVP SPPKTRSSKK TSDILTTTQP TIAESSEPKV RHVNDDNVSS TPRAHSSKKN 540
KSTRKNDDNI PSPPKTRSSK KTSNILATTQ PAKAEPSEPK VTRVSRRKEL HAERCEAKRL 600
ERLKGRQFYH SQTMQPITFE QVMSNEDSEN ETDDYALDIS ERLRLERLVG VSKEEKRYMY 660
LWNIFVRKQR VIADGHVPWA CEEFAKLHKE EMKNSSSFDW WWRMFRIKLW NNGLICAKTF 720
HKCTTILLSN SDEAGQFTSG SAANANNQQS MEVDE 755 
Gene Ontology
GO:0005634; C: nucleus; IDA: TAIR
GO:0046872; F: metal ion binding; IEA: UniProtKB-KW
GO:0003700; F: sequence-specific DNA binding transcription factor activity; ISS: TAIR
GO:0006306; P: DNA methylation; IEP: TAIR
GO:0007275; P: multicellular organismal development; IEA: UniProtKB-KW
GO:2000014; P: regulation of endosperm development; IMP: TAIR
GO:0006349; P: regulation of gene expression by genetic imprinting; IEP: TAIR
GO:0006351; P: transcription, DNA-templated; IEA: UniProtKB-KW 
Interpro
InterPro; IPR019135; Polycomb_protein_VEFS-Box
InterPro; IPR015880; Znf_C2H2-like
Pfam
Pfam; PF09733; VEFS-Box 
SMART
SMART; SM00355; ZnF_C2H2 
PROSITE
PS00028; ZINC_FINGER_C2H2_1 
PRINTS