※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
8.54 
Molecular Weight
35804.46 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Malate dehydrogenase 1, mitochondrial; mNAD-MDH 1 
Gene Name
At1g53240; F12M16.14 
Created Date
2000-12-01 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
26
RRSFSSGSVPERKVA
dbPPT, P3DB, PhosPhAt
[6, 7]
23
AVIRRSFSSGSVPER
dbPPT, P3DB, PhosPhAt
[1, 2, 3, 5, 6, 7]
235
LTALTKRTQDGGTEV
dbPPT, P3DB, PhosPhAt
[8]
131
GIVKNLCTAIAKYCP
dbPPT, P3DB, PhosPhAt
[3, 4, 7]
314
VLDLGPLSDFEKEGL
dbPPT, P3DB, PhosPhAt
[2, 3, 5, 7]
24
VIRRSFSSGSVPERK
dbPPT, P3DB, PhosPhAt
[2, 3, 5, 6, 7]
21
KQAVIRRSFSSGSVP
dbPPT, P3DB, PhosPhAt
[6, 7]
Functional Description
 
Sequence Annotation
transit peptide 1 22 Mitochondrion
chain 23 341 Malate dehydrogenase 1, mitochondrial
nucleotide phosphate-binding region 36 42 NAD
nucleotide phosphate-binding region 145 147 NAD
active site 205 Proton acceptor
binding site 62 NAD
binding site 109 Substrate
binding site 115 Substrate
binding site 122 NAD
binding site 147 Substrate
binding site 181 Substrate
binding site 256 NAD
Keyword
Complete proteome,Direct protein sequencing,Mitochondrion,NAD,Oxidoreductase,Reference proteome,Transit peptide,Tricarboxylic acid cycle 
Sequence Source
UniProt 
Protein Sequence
MFRSMLVRSS ASAKQAVIRR SFSSGSVPER KVAILGAAGG IGQPLALLMK LNPLVSSLSL 60
YDIANTPGVA ADVGHINTRS EVVGYMGDDN LAKALEGADL VIIPAGVPRK PGMTRDDLFN 120
INAGIVKNLC TAIAKYCPHA LINMISNPVN STVPIAAEIF KKAGMYDEKK LFGVTTLDVV 180
RARTFYAGKA NVPVAEVNVP VIGGHAGVTI LPLFSQATPQ ANLSSDILTA LTKRTQDGGT 240
EVVEAKAGKG SATLSMAYAG ALFADACLKG LNGVPDVIEC SYVQSTITEL PFFASKVRLG 300
KNGVEEVLDL GPLSDFEKEG LEALKPELKS SIEKGVKFAN Q 341 
Gene Ontology
GO:0048046; C: apoplast; IDA: TAIR
GO:0005618; C: cell wall; IDA: TAIR
GO:0009507; C: chloroplast; IDA: TAIR
GO:0005759; C: mitochondrial matrix; IEA: UniProtKB-SubCell
GO:0005739; C: mitochondrion; IDA: TAIR
GO:0005507; F: copper ion binding; IDA: TAIR
GO:0030060; F: L-malate dehydrogenase activity; IMP: TAIR
GO:0044262; P: cellular carbohydrate metabolic process; IEA: InterPro
GO:0042742; P: defense response to bacterium; IEP: TAIR
GO:0006108; P: malate metabolic process; IEA: InterPro
GO:0046686; P: response to cadmium ion; IEP: TAIR
GO:0009409; P: response to cold; IEP: TAIR
GO:0009651; P: response to salt stress; IEP: TAIR
GO:0006099; P: tricarboxylic acid cycle; IEA: UniProtKB-KW 
Interpro
InterPro; IPR001557; L-lactate/malate_DH
InterPro; IPR022383; Lactate/malate_DH_C
InterPro; IPR001236; Lactate/malate_DH_N
InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C
InterPro; IPR001252; Malate_DH_AS
InterPro; IPR010097; Malate_DH_type1
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF02866; Ldh_1_C
Pfam; PF00056; Ldh_1_N 
SMART
 
PROSITE
PS00068; MDH 
PRINTS