※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
8.93 
Molecular Weight
24161.48 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Casparian strip membrane protein 3 
Gene Name
CASP3; At2g27370; F10A12.5; F12K2.5 
Created Date
2007-10-23 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
8
MDIEKAGSRREEEEP
dbPPT, P3DB, PhosPhAt
[1, 2, 3]
Functional Description
Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion. 
Sequence Annotation
chain 1 221 Casparian strip membrane protein 3
topological domain 1 58 Cytoplasmic
transmembrane region 59 79 Helical;
topological domain 80 109 Extracellular
transmembrane region 110 130 Helical;
topological domain 131 148 Cytoplasmic
transmembrane region 149 169 Helical;
topological domain 170 194 Extracellular
transmembrane region 195 215 Helical;
topological domain 216 221 Cytoplasmic
compositionally biased region 11 14 Poly-Glu
glycosylation site 173 N-linked (GlcNAc...)
Keyword
Cell membrane,Cell wall biogenesis/degradation,Complete proteome,Glycoprotein,Membrane,Reference proteome,Transmembrane,Transmembrane helix 
Sequence Source
UniProt 
Protein Sequence
MDIEKAGSRR EEEEPIVQRP KLDKGKGKAH VFAPPMNYNR IMDKHKQEKM SPAGWKRGVA 60
IFDFVLRLIA AITAMAAAAK MATTEETLPF FTQFLQFQAD YTDLPTMSSF VIVNSIVGGY 120
LTLSLPFSIV CILRPLAVPP RLFLILCDTV MMGLTLMAAS ASAAIVYLAH NGNSSSNWLP 180
VCQQFGDFCQ GTSGAVVASF IAATLLMFLV ILSAFALKRT T 221 
Gene Ontology
GO:0048226; C: Casparian strip; IDA: UniProtKB
GO:0016021; C: integral component of membrane; IEA: UniProtKB-KW
GO:0005886; C: plasma membrane; IDA: UniProtKB
GO:0005515; F: protein binding; IPI: UniProtKB
GO:0042803; F: protein homodimerization activity; IDA: UniProtKB
GO:0042545; P: cell wall modification; IMP: UniProtKB
GO:0007043; P: cell-cell junction assembly; IDA: UniProtKB 
Interpro
InterPro; IPR006702; UPF0497_TM_pln
InterPro; IPR006459; UPF0497_TM_pln_subgr
Pfam
Pfam; PF04535; DUF588 
SMART
 
PROSITE
 
PRINTS