※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||
Theoretical PI | 5.67 | ||||||||||||||||||||||||||||||||||||||
Molecular Weight | 41028.69 | ||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||
Protein Name | E3 ubiquitin-protein ligase RHF2A; RING-H2 zinc finger protein RHF2a | ||||||||||||||||||||||||||||||||||||||
Gene Name | RHF2A; At5g22000; T6G21.110 | ||||||||||||||||||||||||||||||||||||||
Created Date | 2010-07-13 | ||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Probable E3 ubiquitin-protein ligase involved in the positive regulation of the gametogenesis progression. Required for the degradation of KRP6, a cyclin-dependent kinase inhibitor which accumulates during meiosis and blocks the progression of subsequent mitoses during gametophytes development. Functions in association with RHF1A. Sequence Annotation chain 1 375 E3 ubiquitin-protein ligase RHF2A zinc finger region 33 74 RING-type; atypical compositionally biased region 158 278 Ser-rich splice variant 3 6 In isoform 2. Keyword Alternative splicing,Complete proteome,Ligase,Metal-binding,Reference proteome,Ubl conjugation pathway,Zinc,Zinc-finger Sequence Source UniProt Protein Sequence MEGAGETTTS EGHLTSAAAF VEGGIQDACD DACSICLESF CESDPSTLTS CKHEYHLQCI 60 LEWCQRSSQC PMCWQSISLK DPTSQELLEA VEQERNFRFN PTRNATIFRH PTLGDFELQH 120 LPVGVDNAEI EERIIQHLAA AAAMGRARHG VRREGHRSRS SSQGHQQFMV FSSQPNASSP 180 PPHPPMPSSP SQRDESDTVS NLPHNALGEG SHQSNTQPPT SSHPRQVSPS ASDSNSRPLN 240 QSSPSEQDRA GPSELQSFSE SLKSRLNAVS TRYKESISKN TRNWKDRLFS RNTSMADLGS 300 EVKREVSAGI ATVSRMMERL ETRENSRPST ASVSDVSENH TPETNNEHNR AAAGDEHSVN 360 ERGVKETCAT GSGSS 375 Gene Ontology GO:0005886; C: plasma membrane; IDA: TAIR GO:0016874; F: ligase activity; IEA: UniProtKB-KW GO:0008270; F: zinc ion binding; IEA: InterPro GO:0009561; P: megagametogenesis; IGI: TAIR GO:0055046; P: microgametogenesis; IGI: TAIR GO:0016567; P: protein ubiquitination; IEA: UniProtKB-UniPathway GO:0051603; P: proteolysis involved in cellular protein catabolic process; IGI: TAIR GO:0051726; P: regulation of cell cycle; IGI: TAIR Interpro Pfam Pfam; PF13639; zf-RING_2 SMART SMART; SM00184; RING PROSITE PS50089; ZF_RING_2 PRINTS |