※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.49 
Molecular Weight
43637.87 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
UDP-D-apiose/UDP-D-xylose synthase 1 
Gene Name
AXS1; At2g27860; F15K20.4 
Created Date
2013-10-16 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
322
EGAIESPTVDVSSKE
dbPPT, PhosPhAt
[2, 3]
320
SGEGAIESPTVDVSS
dbPPT, PhosPhAt
[1, 2, 3]
Functional Description
Catalyzes the conversion of UDP-D-glucuronate to a mixture of UDP-D-apiose and UDP-D-xylose. D-Apiose (3-C-hydroxymethyl-d-erythrose) is the only plant cell wall monosaccharide with a branched carbon skeleton and is found in rhamnogalacturonan II (RG-II), apiogalacturonan, and several apioglycosides. 
Sequence Annotation
chain 1 389 UDP-D-apiose/UDP-D-xylose synthase 1
nucleotide phosphate-binding region 49 80 NAD
nucleotide phosphate-binding region 185 189 NAD
nucleotide phosphate-binding region 236 240 Substrate
nucleotide phosphate-binding region 253 260 Substrate
nucleotide phosphate-binding region 337 341 Substrate
active site 185 Proton acceptor
binding site 182 Substrate
binding site 214 Substrate
binding site 235 NAD
Keyword
Cell wall biogenesis/degradation,Complete proteome,Cytoplasm,NAD,Reference proteome 
Sequence Source
UniProt 
Protein Sequence
MANGANRVDL DGKPIQPLTI CMIGAGGFIG SHLCEKLLTE TPHKVLALDV YNDKIKHLLE 60
PDTVEWSGRI QFHRINIKHD SRLEGLVKMA DLIINLAAIC TPADYNTRPL DTIYSNFIDA 120
LPVVKYCSEN NKRLIHFSTC EVYGKTIGSF LPKDHPLRDD PAFYVLKEDI SPCIFGSIEK 180
QRWSYACAKQ LIERLVYAEG AENGLEFTIV RPFNWIGPRM DFIPGIDGPS EGVPRVLACF 240
SNNLLRREPL KLVDGGESQR TFVYINDAIE AVLLMIENPE RANGHIFNVG NPNNEVTVRQ 300
LAEMMTEVYA KVSGEGAIES PTVDVSSKEF YGEGYDDSDK RIPDMTIINR QLGWNPKTSL 360
WDLLESTLTY QHRTYAEAVK KATSKPVAS 389 
Gene Ontology
GO:0005737; C: cytoplasm; NAS: TAIR
GO:0005829; C: cytosol; IDA: TAIR
GO:0051287; F: NAD binding; IDA: TAIR
GO:0048040; F: UDP-glucuronate decarboxylase activity; IDA: TAIR
GO:0009226; P: nucleotide-sugar biosynthetic process; IDA: TAIR 
Interpro
InterPro; IPR001509; Epimerase_deHydtase
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF01370; Epimerase 
SMART
 
PROSITE
 
PRINTS