※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
8.28 
Molecular Weight
31049.98 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Probable aquaporin PIP2-6; Plasma membrane intrinsic protein 2-6; AtPIP2;6; Plasma membrane intrinsic protein 2e; PIP2e; Probable aquaporin PIP2-6, N-terminally processed 
Gene Name
PIP2-6; PIP2E; At2g39010; T7F6.18 
Created Date
2003-06-27 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
7
*MTKDELTEEESLSG
dbPPT, P3DB, PhosPhAt
[1, 13, 14, 2, 4, 5, 7]
13
LTEEESLSGKDYLDP
dbPPT, P3DB, PhosPhAt
[1, 13, 14, 2, 3, 5, 7, 8]
2
******MTKDELTEE
dbPPT, P3DB, PhosPhAt
[13, 2]
277
RAGAMKAYGSVRSQL
dbPPT, P3DB, PhosPhAt
[14, 7, 9]
11
DELTEEESLSGKDYL
dbPPT, P3DB, PhosPhAt
[1, 12, 13, 14, 2, 3, 4, 5, 6, 7, 8]
282
KAYGSVRSQLHELHA
dbPPT, P3DB, PhosPhAt
[1, 10, 11, 12, 13, 14, 2, 5, 6, 7, 9]
17
ESLSGKDYLDPPPVK
dbPPT, P3DB, PhosPhAt
[13, 2]
279
GAMKAYGSVRSQLHE
dbPPT, P3DB, PhosPhAt
[1, 10, 13, 14]
Functional Description
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity). 
Sequence Annotation
chain 1 289 Probable aquaporin PIP2-6
initiator methionine 1 Removed; alternate
chain 2 289 Probable aquaporin PIP2-6, N-terminally processed
topological domain 1 38 Cytoplasmic
transmembrane region 39 59 Helical; Name=1;
topological domain 60 80 Extracellular
transmembrane region 81 101 Helical; Name=2;
topological domain 102 124 Cytoplasmic
transmembrane region 125 145 Helical; Name=3;
topological domain 146 165 Extracellular
transmembrane region 166 186 Helical; Name=4;
topological domain 187 200 Cytoplasmic
transmembrane region 201 221 Helical; Name=5;
topological domain 222 248 Extracellular
transmembrane region 249 269 Helical; Name=6;
topological domain 270 289 Cytoplasmic
short sequence motif 106 108 NPA 1
short sequence motif 227 229 NPA 2
modified residue 1 N-acetylmethionine
modified residue 7 Phosphothreonine
modified residue 11 Phosphoserine
modified residue 279 Phosphoserine
modified residue 282 Phosphoserine
Keyword
Acetylation,Cell membrane,Complete proteome,Membrane,Phosphoprotein,Reference proteome,Repeat,Transmembrane,Transmembrane helix,Transport 
Sequence Source
UniProt 
Protein Sequence
MTKDELTEEE SLSGKDYLDP PPVKTFEVRE LKKWSFYRAV IAEFIATLLF LYVTVLTVIG 60
FKSQTDINAG GGACASVGLL GISWAFGGMI FILVYCTAGI SGGHINPAVT FGLFLASKVS 120
LVRAVSYMVA QCLGATCGVG LVKVFQSTYY NRYGGGANML SDGYNVGVGV GAEIIGTFVL 180
VYTVFSATDP KRNARDSHIP VLAPLPIGFS VFMVHLATIP ITGTGINPAR SFGAAVIYNN 240
QKAWDDQWIF WVGPFVGAAI AAFYHQFVLR AGAMKAYGSV RSQLHELHA 289 
Gene Ontology
GO:0016021; C: integral component of membrane; IEA: UniProtKB-KW
GO:0016020; C: membrane; IDA: TAIR
GO:0005886; C: plasma membrane; IDA: TAIR
GO:0015250; F: water channel activity; ISS: TAIR
GO:0009624; P: response to nematode; IEP: TAIR 
Interpro
InterPro; IPR023271; Aquaporin-like
InterPro; IPR000425; MIP
InterPro; IPR022357; MIP_CS
Pfam
Pfam; PF00230; MIP 
SMART
 
PROSITE
PS00221; MIP 
PRINTS
PR00783; MINTRINSICP