※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||
Theoretical PI | 6.23 | ||||||||||||||||||||||||||||||
Molecular Weight | 54001.2 | ||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||
Protein Name | Regulatory protein NPR5; BTB/POZ domain-containing protein NPR5; Protein BLADE ON PETIOLE 2 | ||||||||||||||||||||||||||||||
Gene Name | NPR5; BOP2; At2g41370; F13H10.8 | ||||||||||||||||||||||||||||||
Created Date | 2011-05-03 | ||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB1/FIL and YAB3, and through positive regulation of LOB domain-containing genes LOB, LBD6/AS2 and LBD36. Promotes and maintains a developmentally determinate state in leaf cells through the negative regulation of JAG, JGL and class I KNOX genes. Is also involved in nectary development, formation of normal abscission zones and suppression of bract formation. Sequence Annotation chain 1 491 Regulatory protein NPR5 domain 26 116 BTB repeat 254 283 ANK 1 repeat 284 313 ANK 2 repeat 318 347 ANK 3 compositionally biased region 403 435 Asn-rich compositionally biased region 472 490 His-rich Keyword ANK repeat,Complete proteome,Cytoplasm,Nucleus,Reference proteome,Repeat,Ubl conjugation pathway Sequence Source UniProt Protein Sequence MSNLEESLRS LSLDFLNLLI NGQAFSDVTF SVEGRLVHAH RCILAARSLF FRKFFCGTDS 60 PQPVTGIDPT QHGSVPASPT RGSTAPAGII PVNSVGYEVF LLLLQFLYSG QVSIVPQKHE 120 PRPNCGERGC WHTHCSAAVD LALDTLAASR YFGVEQLALL TQKQLASMVE KASIEDVMKV 180 LIASRKQDMH QLWTTCSHLV AKSGLPPEIL AKHLPIDVVT KIEELRLKSS IARRSLMPHN 240 HHHDLSVAQD LEDQKIRRMR RALDSSDVEL VKLMVMGEGL NLDESLALHY AVESCSREVV 300 KALLELGAAD VNYPAGPAGK TPLHIAAEMV SPDMVAVLLD HHADPNVRTV GGITPLDILR 360 TLTSDFLFKG AVPGLTHIEP NKLRLCLELV QSAAMVISRE EGNNSNNQNN DNNTGIYPHM 420 NEEHNSGSSG GSNNNLDSRL VYLNLGAGTG QMGPGRDQGD DHNSQREGMS RHHHHHQDPS 480 TMYHHHHQHH F 491 Gene Ontology GO:0005737; C: cytoplasm; IDA: TAIR GO:0005634; C: nucleus; IDA: TAIR GO:0005515; F: protein binding; IPI: UniProtKB GO:0010434; P: bract formation; IGI: UniProtKB GO:0010582; P: floral meristem determinacy; IGI: TAIR GO:0010227; P: floral organ abscission; IGI: UniProtKB GO:0048439; P: flower morphogenesis; IGI: TAIR GO:0009864; P: induced systemic resistance, jasmonic acid mediated signaling pathway; IGI: TAIR GO:0010254; P: nectary development; IGI: TAIR GO:0009944; P: polarity specification of adaxial/abaxial axis; IGI: TAIR GO:0016567; P: protein ubiquitination; IEA: UniProtKB-UniPathway GO:0009954; P: proximal/distal pattern formation; IGI: TAIR Interpro Pfam SMART PROSITE PRINTS |