※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Theoretical PI | 8.41 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight | 81097.88 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Serrate RNA effector molecule | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | SE; At2g27100; T20P8.15 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Created Date | 2009-09-22 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Acts as a mediator between the cap-binding complex (CBC) and both the pre-mRNA splicing and primary microRNAs (miRNAs) processing machinery. Required for proper processing of primary miRNAs to miRNAs, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Does not participate in sense post-transcriptional gene silencing. Acts as a regulator of meristem activity and adaxial leaf fate via the miRNA gene-silencing pathway by regulating the expression of PHB and by limiting the competence of shoot tissue to respond to KNOX expression. Its function is however not limited to miRNA-mediated repression of leaf polarity genes, but rather acts as a general regulator of primary microRNAs processing. Also critical for the accumulation of the trans-acting small interfering RNA (ta-siRNA). Required for pre-mRNA splicing. Sequence Annotation chain 1 720 Serrate RNA effector molecule zinc finger region 498 523 C2H2-type compositionally biased region 25 111 Pro-rich compositionally biased region 121 182 Gly-rich compositionally biased region 562 598 Arg-rich compositionally biased region 629 690 Pro-rich modified residue 76 Phosphoserine modified residue 90 Phosphoserine modified residue 92 Phosphoserine modified residue 689 Phosphoserine helix 198 201 helix 202 204 turn 205 207 helix 211 237 helix 241 247 helix 249 275 strand 283 286 helix 331 333 helix 336 357 strand 386 388 strand 395 397 helix 400 414 helix 418 420 helix 446 460 helix 464 469 helix 471 482 helix 483 485 strand 486 490 strand 492 500 strand 502 504 strand 508 511 helix 512 522 helix 524 543 Keyword 3D-structure,Complete proteome,Metal-binding,mRNA processing,mRNA splicing,Nucleus,Phosphoprotein,Reference proteome,RNA-mediated gene silencing,Zinc,Zinc-finger Sequence Source UniProt Protein Sequence MADVNLPPSD SVDNRLPEKS TSSSPPPPPP SSSLPQQEQE QDQQQLPLRR ERDSRERRDE 60 RDIERPPPNR RERDRSPLPP PRRDYKRRPS LSPPPPYRDR RHSPPQRRSP PQKRYRRDDN 120 GYDGRRGSPR GGYGPPDRRF GYDHGGGYDR EMGGRPGYGD ERPHGRFMGR YQDWEGGRGG 180 YGDASNSGNP QRDGLMSYKQ FIQELEDDIL PSEAERRYQE YKSEYITTQK RAFFNTHKEE 240 DWLKNKYHPT NLLSVIERRN DLAQKVAKDF LLDLQSGTLD LGPAVTALNK SGRTSEPNSE 300 DEAAGVGKRK RHGMGGAKEN ELLSAAPKAP SFTSDPKRIL TDVEQTQALV RKLDSEKKIE 360 ENVLQGSETE KSGREKLHSG STGPVVIIRG LTSVKGLEGV ELLDTLVTYL WRVHGLDYYG 420 KVETNEAKGL RHVRAEGKVS DAKGDENESK FDSHWQERLK GQDPLEVMAA KEKIDAAATE 480 ALDPHVRKIR DEKYGWKYGC GAKGCTKLFH AAEFVYKHLK LKHTELVTEL TTKVREELYF 540 QNYMNDPNAP GGQPATQQSG PRDRPIRRKP SMENRLRDDR GGRRERDGRA NGNDRNDRSE 600 DQQRGDNDGG NPGEVGYDAF GGQGGVHVPP FLSDINPPPM LMPVPGAGPL GPFVPAPPEV 660 AMQMFRDPSG PNPPFEGSGR GGPAPFLLSP AFRQDPRRLR SYQDLDAPEE EVTVIDYRSL 720 Gene Ontology GO:0009507; C: chloroplast; IDA: TAIR GO:0005829; C: cytosol; IDA: TAIR GO:0010445; C: nuclear dicing body; IDA: UniProtKB GO:0016607; C: nuclear speck; IDA: TAIR GO:0005730; C: nucleolus; IDA: TAIR GO:0005634; C: nucleus; IDA: TAIR GO:0003677; F: DNA binding; ISS: TAIR GO:0046872; F: metal ion binding; IEA: UniProtKB-KW GO:0005515; F: protein binding; IPI: UniProtKB GO:0003700; F: sequence-specific DNA binding transcription factor activity; ISS: TAIR GO:0016568; P: chromatin modification; TAS: TAIR GO:0006397; P: mRNA processing; IEA: UniProtKB-KW GO:0031053; P: primary miRNA processing; IMP: UniProtKB GO:0010267; P: production of ta-siRNAs involved in RNA interference; IMP: TAIR GO:2000011; P: regulation of adaxial/abaxial pattern formation; IMP: TAIR GO:0048509; P: regulation of meristem development; IMP: TAIR GO:0006355; P: regulation of transcription, DNA-templated; TAS: TAIR GO:0008380; P: RNA splicing; IMP: UniProtKB GO:0048367; P: shoot system development; IMP: TAIR Interpro Pfam SMART SMART; SM00355; ZnF_C2H2 PROSITE PS00028; ZINC_FINGER_C2H2_1 PRINTS |