※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||||||||||
Theoretical PI | 5.8 | ||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight | 105986.52 | ||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Pumilio homolog 3; APUM-3; AtPUM3 | ||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | APUM3; At2g29140; F16P2.48 | ||||||||||||||||||||||||||||||||||||||||||||||
Created Date | 2010-11-30 | ||||||||||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. Sequence Annotation chain 1 964 Pumilio homolog 3 domain 606 946 PUM-HD repeat 626 661 Pumilio 1 repeat 662 697 Pumilio 2 repeat 698 733 Pumilio 3 repeat 734 769 Pumilio 4 repeat 770 806 Pumilio 5 repeat 807 842 Pumilio 6 repeat 843 878 Pumilio 7 repeat 879 920 Pumilio 8 modified residue 192 Phosphoserine modified residue 257 Phosphothreonine Keyword Complete proteome,Cytoplasm,Phosphoprotein,Reference proteome,Repeat,RNA-binding,Translation regulation Sequence Source UniProt Protein Sequence MMIPELGRRP MHRGNEDSSF GDDYEKEIGV LLGEQQRRQV EADELERELN LYRSGSAPPT 60 VDGSLSAAGG LFSGGGGASF LEFGGVNKGN GFGGDDEEFR KDPAYLSYYY ANMKLNPRLP 120 PPLMSREDLR VAQRLKGSNN VLGGVGDRRK VNDSRSLFSM PPGFEAGKPG ASASEWDANG 180 LIGLGLGGKQ KSFADIFQAD MGHPVVQQPS RPASRNTFDE NVDSNNNLSP SASQGIGAPS 240 PYCYAAVLGS SLSRNGTPDP QGIARVPSPC LTPIGSGRVS SNDKRNTSNQ SPFNGVTSGL 300 NESSDLVNAL SGLNLSGTGG LDERGQAEQD VEKVRNYMFG LQDGHNEVNP HGFPNRSDQA 360 RGTASCRNSQ MRGSQGSAYN SGSGVANPYQ HHDSPNYYAL NPAVASMMAN QLGTNNYSPM 420 YENASATLGY SAMDSRLHGG SFVSSGQNLS ESRNIGRVGN RMMEGGTGHP SHLADPMYHQ 480 YARFSENADS FDLLNDPSMD RNYGNSYMNM LEIQRAYLGS QKSQYGLPYK SGSPNSHSYY 540 GSPTFGSNMS YPGSPLAHHG MPNSLMSPYS PMRRGEVNMR YPAATRNYTG GVMGSWHMDA 600 SLDEGFGSSM LEEFKSNKTR GFELSEIAGH VVEFSSDQYG SRFIQQKLET ATTDEKNMVY 660 EEIMPKALAL MTDVFGNYVI QKFFEHGLPP QRRELGEKLI DNVLPLSLQM YGCRVIQKAI 720 EVVDLDQKIQ MVKELDGHVM RCVRDQNGNH VVQKCIECVP EENIEFIIST FFGHVVTLST 780 HPYGCRVIQR VLEHCHNPDT QSKVMEEILS TVSMLTQDQY GNYVVQHVLE HGKPDERTVI 840 IKELAGKIVQ MSQQKFASNV VEKCLTFGGP EERELLVNEM LGTTDENEPL QAMMKDQFAN 900 YVVQKVLETC DDQQRELILT RIKVHLNALK KYTYGKHIVA RVEKLVAAGE RRMALQSLPQ 960 PLVA 964 Gene Ontology GO:0005737; C: cytoplasm; IEA: UniProtKB-SubCell GO:0005886; C: plasma membrane; IDA: TAIR GO:0003729; F: mRNA binding; IDA: UniProtKB GO:0006417; P: regulation of translation; IEA: UniProtKB-KW Interpro Pfam SMART SMART; SM00025; Pumilio PROSITE PRINTS |