※ dbPPT Protein Information
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UniProt Accession | |||||||||||||||||||||||||||||||||||||||||||||||
Theoretical PI | 5.74 | ||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight | 106563.42 | ||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | |||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | |||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Pumilio homolog 1; APUM-1; AtPUM1 | ||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | APUM1; At2g29200; F16P2.42 | ||||||||||||||||||||||||||||||||||||||||||||||
Created Date | 2010-11-30 | ||||||||||||||||||||||||||||||||||||||||||||||
Organism | Arabidopsis thaliana(Mouse-ear cress) | ||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 3702 | ||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
Functional Description Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. Sequence Annotation chain 1 968 Pumilio homolog 1 domain 610 950 PUM-HD repeat 630 665 Pumilio 1 repeat 666 701 Pumilio 2 repeat 702 737 Pumilio 3 repeat 738 773 Pumilio 4 repeat 774 810 Pumilio 5 repeat 811 846 Pumilio 6 repeat 847 882 Pumilio 7 repeat 883 924 Pumilio 8 modified residue 194 Phosphoserine modified residue 261 Phosphothreonine Keyword Complete proteome,Cytoplasm,Phosphoprotein,Reference proteome,Repeat,RNA-binding,Translation regulation Sequence Source UniProt Protein Sequence MIPELGRRPM HRGNEDSSFG DDYEKEIGVL LGEQQRRQVE ADELERELNL FRSGSAPPTV 60 DGSVSAAGGL FSGGGGAPFL EFGGVNKGNG FGGDDEEFRK DPAYLSYYYA NMKLNPRLPP 120 PLMSREDLRV AQRLKGSNNV LGGVGDRRKV NDNRSLFSMP PGFEGEKTGA SASEWDANGL 180 IGLPGLGLGG KQKSFADIFQ ADMGHGHPVA QQPSRPASRN TFDENVDSNN NLSPSASQGI 240 GAPSPYSYAA VLGSSLSRNG TPDPQAIARV PSPCLTPIGS GRMSSNDKRN TSNQSPFNGV 300 TSGLNESSDL VNALSGLNLS CSVGLDDRSQ AEQDVEKVRN YMFGLQGGHN EVNQHEFPNK 360 SDQAHKATGS LRNSQLRGPH GSAYNGGVGL ANPYQQLDSP NYCLNNYALN PAVASMMANQ 420 LGNNNFAPMY DNVSALGFSG MDSRHHGRGF VSSGQNLSES RNLGRFSNRM MGGGAGLQSH 480 MVDPMYNQYA DSLDLLNDPS MDRNFMGGSS YMDMLELQRA YLGAQKSQYG VPYKSGSPNS 540 HSYYGSPTFG SNMSYPGSPL AHHGMPNSLM SPYSPMRRDE VNMRFPSATR NYSGGLMGSW 600 HMDASFDEGF GSSMLEEFKS NKTRGFELSE IAGHVVEFSS DQYGSRFIQQ KLETATTDEK 660 NMVYEEIMPQ ALVLMTDVFG NYVIQKFFEH GLPPQRRELA EKLFDHVLPL SLQMYGCRVI 720 QKAIEVVDLD QKIKMVKELD GHVMRCVRDQ NGNHVVQKCI ECVPEENIEF IISTFFGHVV 780 TLSTHPYGCR VIQRVLEHCH DPDTQSKVME EILSTVSMLA QDQYGNYVVQ HVLEHGKPDE 840 RTVIIKELAG KIVQMSQQKF ASNVVEKCLT FGGPEERELL VNEMLGTTDE NEPLQAMMKD 900 QFANYVVQKV LETCDDQQRE LILTRIKVHL TALKKYTYGK HVVARIEKLV AAGERRMALQ 960 SLTQPQMA 968 Gene Ontology GO:0005737; C: cytoplasm; IEA: UniProtKB-SubCell GO:0003729; F: mRNA binding; IDA: UniProtKB GO:0006417; P: regulation of translation; IEA: UniProtKB-KW Interpro Pfam SMART SMART; SM00025; Pumilio PROSITE PRINTS |