※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
6.17 
Molecular Weight
72578.09 
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Two-component response regulator ARR2; Receiver-like protein 5 
Gene Name
ARR2; ARP5; At4g16110; dl4095w; FCAALL.297 
Created Date
2004-07-19 
Organism
Arabidopsis thaliana(Mouse-ear cress) 
NCBI Taxa ID
3702 
Phosphorylation Sites
Position
Peptide
Source
References
446
NSIPETNSRVLPTTH
dbPPT, PhosPhAt
[3]
588
EHGQNLQSPSRNLYH
dbPPT, PhosPhAt
[1, 2]
Functional Description
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. 
Sequence Annotation
chain 1 664 Two-component response regulator ARR2
domain 29 144 Response regulatory
DNA-binding region 218 268 Myb-like GARP
short sequence motif 215 218 Nuclear localization signal
compositionally biased region 279 664 Gln-rich
modified residue 80 4-aspartylphosphate
Keyword
Activator,Complete proteome,Cytokinin signaling pathway,DNA-binding,Ethylene signaling pathway,Nucleus,Phosphoprotein,Reference proteome,Transcription,Transcription regulation,Two-component regulatory system 
Sequence Source
UniProt 
Protein Sequence
MVNPGHGRGP DSGTAAGGSN SDPFPANLRV LVVDDDPTCL MILERMLMTC LYRVTKCNRA 60
ESALSLLRKN KNGFDIVISD VHMPDMDGFK LLEHVGLEMD LPVIMMSADD SKSVVLKGVT 120
HGAVDYLIKP VRIEALKNIW QHVVRKKRNE WNVSEHSGGS IEDTGGDRDR QQQHREDADN 180
NSSSVNEGNG RSSRKRKEEE VDDQGDDKED SSSLKKPRVV WSVELHQQFV AAVNQLGVDK 240
AVPKKILEMM NVPGLTRENV ASHLQKYRIY LRRLGGVSQH QGNMNHSFMT GQDQSFGPLS 300
SLNGFDLQSL AVTGQLPPQS LAQLQAAGLG RPTLAKPGMS VSPLVDQRSI FNFENPKIRF 360
GDGHGQTMNN GNLLHGVPTG SHMRLRPGQN VQSSGMMLPV ADQLPRGGPS MLPSLGQQPI 420
LSSSVSRRSD LTGALAVRNS IPETNSRVLP TTHSVFNNFP ADLPRSSFPL ASAPGISVPV 480
SVSYQEEVNS SDAKGGSSAA TAGFGNPSYD IFNDFPQHQQ HNKNISNKLN DWDLRNMGLV 540
FSSNQDAATA TATAAFSTSE AYSSSSTQRK RRETDATVVG EHGQNLQSPS RNLYHLNHVF 600
MDGGSVRVKS ERVAETVTCP PANTLFHEQY NQEDLMSAFL KQEGIPSVDN EFEFDGYSID 660
NIQV 664 
Gene Ontology
GO:0005634; C: nucleus; IDA: TAIR
GO:0003682; F: chromatin binding; IEA: InterPro
GO:0003677; F: DNA binding; IEA: UniProtKB-KW
GO:0000156; F: phosphorelay response regulator activity; ISS: TAIR
GO:0005515; F: protein binding; IPI: IntAct
GO:0003700; F: sequence-specific DNA binding transcription factor activity; IDA: TAIR
GO:0071368; P: cellular response to cytokinin stimulus; IMP: TAIR
GO:0009736; P: cytokinin-activated signaling pathway; TAS: TAIR
GO:0009873; P: ethylene-activated signaling pathway; IMP: TAIR
GO:0035556; P: intracellular signal transduction; ISS: GOC
GO:0010150; P: leaf senescence; IMP: UniProtKB
GO:0010082; P: regulation of root meristem growth; IMP: TAIR
GO:0080113; P: regulation of seed growth; IMP: TAIR
GO:0010119; P: regulation of stomatal movement; IMP: TAIR
GO:0009735; P: response to cytokinin; IGI: TAIR
GO:0009723; P: response to ethylene; IMP: TAIR
GO:0048364; P: root development; IMP: TAIR
GO:0006351; P: transcription, DNA-templated; IEA: UniProtKB-KW 
Interpro
InterPro; IPR011006; CheY-like_superfamily
InterPro; IPR009057; Homeodomain-like
InterPro; IPR017930; Myb_dom
InterPro; IPR006447; Myb_dom_plants
InterPro; IPR017053; Response_reg_B-typ_pln
InterPro; IPR001005; SANT/Myb
InterPro; IPR001789; Sig_transdc_resp-reg_receiver
Pfam
Pfam; PF00249; Myb_DNA-binding
Pfam; PF00072; Response_reg 
SMART
SMART; SM00448; REC 
PROSITE
PS51294; HTH_MYB
PS50110; RESPONSE_REGULATORY 
PRINTS