※ dbPPT Protein Information

TagContent
UniProt Accession
Theoretical PI
5.48 
Molecular Weight
40632.64 
Genbank Protein ID
 
Genbank Nucleotide ID
 
Protein Name
Homoserine dehydrogenase; HDH 
Gene Name
 
Created Date
2014-03-19 
Organism
Triticum aestivum(Wheat) 
NCBI Taxa ID
4565 
Phosphorylation Sites
Position
Peptide
Source
References
80
CSAKSAGSPLSSLLA
dbPPT
[1]
Functional Description
 
Sequence Annotation
nucleotide phosphate-binding region 16 21 NADP
active site 245 Proton donor
binding site 146 NADP
binding site 230 Substrate
Keyword
Amino-acid biosynthesis,Branched-chain amino acid biosynthesis,Complete proteome,Isoleucine biosynthesis,Methionine biosynthesis,NADP,Oxidoreductase,Threonine biosynthesis 
Sequence Source
UniProt 
Protein Sequence
MPQAQARAVL PVVLLGCGGV GRHLLRHIVS CRSLHANQGV AIRVVGVADS SSLLVADDVR 60
ASGLDDALLN DLCSAKSAGS PLSSLLARGH CQVFNKPEAM GKVIDAATML GRTTGLVIVD 120
CSATYDTVGV LKDAVDHGCC VVLANKKPLT CAYEDFKKLT SHFRQIRFES TVGAGLPVIA 180
SVTRIIASGD PVSRIVGSLS GTLGYVMSEL EDGNFFSEVV KTAKALGYTE PDPRDDLSGM 240
DVARKALILA RLLGQQISME NINVESLYPS ELGPEVMSTT DFLESGLAKL DETIEEKVKA 300
ASLRGNVLRY VCVIGKTGCQ VGLQEVPKDS ALGRLRGSDN VVEIYSRCYE SSPLVIQGAG 360
AGNDTTAAGV LADIIDLQDL FQARP 385 
Gene Ontology
GO:0004412; F: homoserine dehydrogenase activity; IEA: UniProtKB-EC
GO:0050661; F: NADP binding; IEA: InterPro
GO:0009097; P: isoleucine biosynthetic process; IEA: UniProtKB-KW
GO:0009086; P: methionine biosynthetic process; IEA: UniProtKB-KW
GO:0009088; P: threonine biosynthetic process; IEA: UniProtKB-KW 
Interpro
InterPro; IPR005106; Asp/hSer_DH_NAD-bd
InterPro; IPR001342; HDH_cat
InterPro; IPR019811; HDH_CS
InterPro; IPR022697; HDH_short
InterPro; IPR016040; NAD(P)-bd_dom
Pfam
Pfam; PF00742; Homoserine_dh
Pfam; PF03447; NAD_binding_3 
SMART
 
PROSITE
PS01042; HOMOSER_DHGENASE 
PRINTS